Genotoxic risk assessment of pathology and anatomy laboratory workers exposed to formaldehyde by use of personal air sampling and analysis of DNA damage in peripheral lymphocytes

• Published in: Mutation research Vol. 605; no. 1; pp. 30 - 41
• Main Authors: Orsière, T., Sari-Minodier, I., Iarmarcovai, G., Botta, A.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 16.06.2006; Elsevier
• Subjects: Adult; Biological and medical sciences; Case-Control Studies; Centromere-micronucleus assay; Chemiluminescence microplate assay; DNA Damage; Female; Formaldehyde - toxicity; Fundamental and applied biological sciences. Psychology; Genetics of eukaryotes. Biological and molecular evolution; Humans; In Situ Hybridization, Fluorescence; Laboratory Personnel; Leukocytes, Mononuclear - drug effects; Leukocytes, Mononuclear - metabolism; Leukocytes, Mononuclear - pathology; Male; Medical sciences; Micronucleus Tests; Middle Aged; Mutagens - toxicity; Occupational Exposure; Pathology Department, Hospital; Personal air sampling; Respiratory Tract Absorption; Risk Assessment; Toxicology; MN; Chemiluminescence microplate assay; BMCR; Personal air sampling; Centromere-micronucleus assay; S.D; C x + MN; Occupational exposure; ELV; STEL; 3D; DPC; PEL; FISH; C − MN; C + MN; C1 + MN; CBMN; MEV; TWA; Air; Risk analysis; Formaldehyde; Toxicology; DNA; Genetics; Lesion; Sampling; Lymphocyte

A study was conducted to evaluate the genotoxic effect of occupational exposure to formaldehyde on pathology and anatomy laboratory workers. The level of exposure to formaldehyde was determined by use of passive air-monitoring badges clipped near the breathing zone of 59 workers for a total sampling...