Voluntary Binge-like Ethanol Consumption Site-specifically Increases c-Fos Immunoexpression in Male C57BL6/J Mice

• Published in: Neuroscience Vol. 367; pp. 159 - 168
• Main Authors: Burnham, Nathan W., Thiele, Todd E.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 26.12.2017
• Subjects: Alcohol Drinking - metabolism; Alcohol Drinking - pathology; Alcohol Drinking - physiopathology; Animals; binge; Binge Drinking - pathology; Brain - drug effects; Brain - metabolism; c-Fos; Central Nervous System Depressants - pharmacology; drinking-in-the-dark (DID); ethanol; Ethanol - pharmacology; Gene Expression Regulation - drug effects; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos - metabolism; surgery; voluntary consumption; VTA; c-Fos; PVN; hr; PFA; NTS; ethanol; CeMPV; PVT; A2; NPY; voluntary consumption; drinking-in-the-dark (DID); DID; PBS; BEC; lPBn; IR; i.p; dBNST; EW; binge; TH; BLA; CRF; LC; PVA; AcbC; LH; vBNST; CeA; surgery
• ISSN: 0306-4522; 1873-7544; 1873-7544
• DOI: 10.1016/j.neuroscience.2017.10.027

•Binge-induced c-Fos with “drinking in the dark” (DID) procedures was assessed.•Groups with and without prior intracranial surgery were compared.•Differences between surgery conditions suggest a point of caution for c-Fos studies. The assessment of binge ethanol-induced neuronal activation, using c-...