Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach - Inukai, Tatsuya; Watanabe, Rikuto; Murakami, Yoshiki; Cabral, Horacio; Kuroda, Masahiko; Nakamura, Shigeki (Scientific reports, 2025)
Keywords: 631/326/193; 639/925/352/152; Alb1 protein; Antifungal agents; Antifungal Agents - pharmacology; Aspergillosis; Aspergillosis - microbiology; Aspergillus fumigatus; Aspergillus fumigatus - drug effects; Aspergillus fumigatus - genetics; Aspergillus fumigatus - metabolism; Aspergillus fumigatus - pathogenicity; Drug delivery systems; Drug development; Fungal Proteins - genetics; Fungal Proteins - metabolism; Fungi; Humanities and Social Sciences; Humans; Hydrogen peroxide; Hypothesis testing; Leukocytes (neutrophilic); Medical innovations; Melanin; Melanins - metabolism; MicroRNAs; MicroRNAs (miRNAs); MicroRNAs - administration & dosage; MicroRNAs - genetics; miRNA; multidisciplinary; Oxidative stress; Oxidative Stress - drug effects; RNA therapeutics; Science; Science (multidisciplinary); Transfection; Virulence - drug effects; Virulence - genetics; Virulence factors; Virulence Factors - genetics; Virulence Factors - metabolism; Western blotting; Drug delivery systems; MicroRNAs (miRNAs); RNA therapeutics; Aspergillus fumigatus