Pretreatment pain predicts perineural invasion in oral squamous cell carcinoma: A prospective study

• Published in: Oral oncology Vol. 61; pp. 115 - 119
• Main Authors: Yeh, Chien-Fu, Li, Wing-Yin, Chu, Pen-Yuan, Kao, Shou-Yen, Chen, Ya-Wei, Lee, Tsung-Lun, Hsu, Yen-Bin, Yang, Cheng-Chieh, Tai, Shyh-Kuan
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.10.2016
• Subjects: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell - pathology; Female; Hematology, Oncology and Palliative Medicine; Humans; Male; Middle Aged; Mouth Neoplasms - pathology; Oral squamous cell carcinoma; Otolaryngology; Pain; Pain - etiology; Perineural invasion; Peripheral Nerves - pathology; Prospective Studies; Quality of life; Visual analogue scale; Pain; Oral squamous cell carcinoma; Perineural invasion; Visual analogue scale; Quality of life
• ISSN: 1368-8375; 1879-0593; 1879-0593
• DOI: 10.1016/j.oraloncology.2016.07.016

•Perineural invasion is a poor prognostic feature for oral squamous cell carcinoma.•Pretreatment pain and clinical T stage are predictors of perineural invasion.•A regression equation was formed to predict the probability of perineural invasion. Perineural invasion (PNI) is an established poor progn...