Remdesivir, mAb114, REGN-EB3, and ZMapp partially rescue nonhuman primates infected with a low passage Kikwit variant of Ebola virus - Prasad, Abhishek N.; Woolsey, Courtney; Borisevich, Viktoriya; Agans, Krystle N.; Deer, Daniel J.; Geisbert, Joan B.; Harrison, Mack B.; Dobias, Natalie S.; Fenton, Karla A.; Cross, Robert W.; Geisbert, Thomas W. (Nature communications, 2025)
Keywords: 13; 13/51; 631/250/2152/2153/1291; 631/326/22/1295; 631/326/596/2042; 64; Adenosine Monophosphate - analogs & derivatives; Adenosine Monophosphate - pharmacology; Adenosine Monophosphate - therapeutic use; Alanine - analogs & derivatives; Alanine - pharmacology; Alanine - therapeutic use; Animals; Antibodies, Monoclonal - pharmacology; Antibodies, Monoclonal - therapeutic use; Antibodies, Monoclonal, Humanized - pharmacology; Antibodies, Monoclonal, Humanized - therapeutic use; Antiviral Agents - pharmacology; Antiviral Agents - therapeutic use; Disease Models, Animal; Ebola virus; Ebolavirus; Ebolavirus - drug effects; Ebolavirus - genetics; Ebolavirus - immunology; Effectiveness; Female; Health services; Hemorrhagic Fever, Ebola - drug therapy; Hemorrhagic Fever, Ebola - mortality; Hemorrhagic Fever, Ebola - virology; Humanities and Social Sciences; Humans; Macaca mulatta; Male; Monoclonal antibodies; multidisciplinary; Patients; Primates; Science; Science (multidisciplinary); Survival; Viral diseases; Viruses