Synergistic activation of bat SARS-like coronaviruses spike protein by elastase and TMPRSS2 - Yamamoto, Yuichiro; Inoue, Tetsuya; Sugiyama, Naoto; Furukawa, Miyu; Sato, Kaoru; Onodera, Taishi; Takahashi, Yoshimasa; Wakita, Takaji; Fukasawa, Masayoshi; Noguchi, Kohji (Scientific reports, 2025)
Keywords: 631/326; 631/337; ACE2; Amino acids; Angiotensin-converting enzyme 2; Animals; Bat SARS-like coronavirus; Benzamidines - pharmacology; Cells; Chiroptera - virology; Chlorocebus aethiops; Coronaviridae; Coronaviruses; COVID-19; Disease transmission; Elastase; Epidemics; Experiments; Guanidines; Humanities and Social Sciences; Humans; Infections; Infectivity; Inflammation; Khosta-2; Medical research; Middle East respiratory syndrome; multidisciplinary; Pancreatic Elastase - metabolism; Proteases; Proteins; Proteolysis; RaTG13; Respiratory diseases; Sarbecovirus; Science; Science (multidisciplinary); Serine Endopeptidases - metabolism; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Severe acute respiratory syndrome-related coronavirus - metabolism; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - metabolism; Spike protein; Statistical analysis; Thermolysin; Trypsin; Vero Cells; Virus Internalization; Viruses; Zoonoses; Bat SARS-like coronavirus; Elastase; Spike protein; Khosta-2; RaTG13