SARS-CoV-2 virus lacking the envelope and membrane open-reading frames as a vaccine platform - Kuroda, Makoto; Halfmann, Peter J.; Uraki, Ryuta; Yamayoshi, Seiya; Kim, Taksoo; Armbrust, Tammy A.; Spyra, Sam; Dahn, Randall; Babujee, Lavanya; Kawaoka, Yoshihiro (Nature communications, 2025)
Keywords: 631/1647/334/1874/1535; 631/326/590/1867; 631/326/596/4130; Animals; Antibodies, Viral - immunology; CD8 antigen; CD8-Positive T-Lymphocytes - immunology; Coronavirus Envelope Proteins; COVID-19; COVID-19 - immunology; COVID-19 - prevention & control; COVID-19 - virology; COVID-19 Vaccines - administration & dosage; COVID-19 Vaccines - genetics; COVID-19 Vaccines - immunology; Cricetinae; Female; Hamsters; Humanities and Social Sciences; Humans; Immunization; Immunization, Secondary; Immunoglobulin A; Lymphocytes; Lymphocytes T; Membranes; Mesocricetus; mRNA; multidisciplinary; Nucleocapsids; Open reading frames; Open Reading Frames - genetics; Proteins; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; Science; Science (multidisciplinary); Severe acute respiratory syndrome coronavirus 2; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Structural proteins; Vaccination; Vaccines; Vaccines, Attenuated - administration & dosage; Vaccines, Attenuated - genetics; Vaccines, Attenuated - immunology; Viral diseases; Viruses