Evaluation of a new mobile system for protecting immune-suppressed patients against airborne contamination
Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient prot...
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| Published in | American journal of infection control Vol. 35; no. 7; pp. 460 - 466 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Mosby, Inc
01.09.2007
Elsevier |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0196-6553 1527-3296 |
| DOI | 10.1016/j.ajic.2007.02.006 |
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| Abstract | Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient protective environment.
Airborne contamination levels were monitored for different simulated scenarios and under actual clinical conditions. Functional tests were used to challenge the unit under adverse conditions, and a preliminary clinical study with patients and staff present was performed at 2 different French hospitals.
Functional tests demonstrated that the unit can rapidly decontaminate air in the protected zone created by the unit and in the surrounding room. In addition, the protected zone is not sensitive to large disturbances that occur in the room. The clinical study included 4 patients with 150 accumulated days of testing. The protected zone created by the unit systematically provided an environment with undetectable airborne fungal levels (ie, <1 CFU/m
3) regardless of the levels in the room or corridor (
P < .01).
These tests show that the unit can be used to create a mobile protective environment for immune-suppressed patients in a standard hospital setting. |
|---|---|
| AbstractList | Background Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient protective environment. Methods Airborne contamination levels were monitored for different simulated scenarios and under actual clinical conditions. Functional tests were used to challenge the unit under adverse conditions, and a preliminary clinical study with patients and staff present was performed at 2 different French hospitals. Results Functional tests demonstrated that the unit can rapidly decontaminate air in the protected zone created by the unit and in the surrounding room. In addition, the protected zone is not sensitive to large disturbances that occur in the room. The clinical study included 4 patients with 150 accumulated days of testing. The protected zone created by the unit systematically provided an environment with undetectable airborne fungal levels (ie, <1 CFU/m3 ) regardless of the levels in the room or corridor ( P < .01). Conclusions These tests show that the unit can be used to create a mobile protective environment for immune-suppressed patients in a standard hospital setting. Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient protective environment. Airborne contamination levels were monitored for different simulated scenarios and under actual clinical conditions. Functional tests were used to challenge the unit under adverse conditions, and a preliminary clinical study with patients and staff present was performed at 2 different French hospitals. Functional tests demonstrated that the unit can rapidly decontaminate air in the protected zone created by the unit and in the surrounding room. In addition, the protected zone is not sensitive to large disturbances that occur in the room. The clinical study included 4 patients with 150 accumulated days of testing. The protected zone created by the unit systematically provided an environment with undetectable airborne fungal levels (ie, <1 CFU/m 3) regardless of the levels in the room or corridor ( P < .01). These tests show that the unit can be used to create a mobile protective environment for immune-suppressed patients in a standard hospital setting. BACKGROUND: Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient protective environment. METHODS: Airborne contamination levels were monitored for different simulated scenarios and under actual clinical conditions. Functional tests were used to challenge the unit under adverse conditions, and a preliminary clinical study with patients and staff present was performed at 2 different French hospitals. RESULTS: Functional tests demonstrated that the unit can rapidly decontaminate air in the protected zone created by the unit and in the surrounding room. In addition, the protected zone is not sensitive to large disturbances that occur in the room. The clinical study included 4 patients with 150 accumulated days of testing. The protected zone created by the unit systematically provided an environment with undetectable airborne fungal levels (ie, <1 CFU/m(3)) regardless of the levels in the room or corridor (P < .01). CONCLUSIONS: These tests show that the unit can be used to create a mobile protective environment for immune-suppressed patients in a standard hospital setting. Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient protective environment. Airborne contamination levels were monitored for different simulated scenarios and under actual clinical conditions. Functional tests were used to challenge the unit under adverse conditions, and a preliminary clinical study with patients and staff present was performed at 2 different French hospitals. Functional tests demonstrated that the unit can rapidly decontaminate air in the protected zone created by the unit and in the surrounding room. In addition, the protected zone is not sensitive to large disturbances that occur in the room. The clinical study included 4 patients with 150 accumulated days of testing. The protected zone created by the unit systematically provided an environment with undetectable airborne fungal levels (ie, <1 CFU/m(3)) regardless of the levels in the room or corridor (P < .01). These tests show that the unit can be used to create a mobile protective environment for immune-suppressed patients in a standard hospital setting. Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient protective environment.BACKGROUNDInvasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient protective environment.Airborne contamination levels were monitored for different simulated scenarios and under actual clinical conditions. Functional tests were used to challenge the unit under adverse conditions, and a preliminary clinical study with patients and staff present was performed at 2 different French hospitals.METHODSAirborne contamination levels were monitored for different simulated scenarios and under actual clinical conditions. Functional tests were used to challenge the unit under adverse conditions, and a preliminary clinical study with patients and staff present was performed at 2 different French hospitals.Functional tests demonstrated that the unit can rapidly decontaminate air in the protected zone created by the unit and in the surrounding room. In addition, the protected zone is not sensitive to large disturbances that occur in the room. The clinical study included 4 patients with 150 accumulated days of testing. The protected zone created by the unit systematically provided an environment with undetectable airborne fungal levels (ie, <1 CFU/m(3)) regardless of the levels in the room or corridor (P < .01).RESULTSFunctional tests demonstrated that the unit can rapidly decontaminate air in the protected zone created by the unit and in the surrounding room. In addition, the protected zone is not sensitive to large disturbances that occur in the room. The clinical study included 4 patients with 150 accumulated days of testing. The protected zone created by the unit systematically provided an environment with undetectable airborne fungal levels (ie, <1 CFU/m(3)) regardless of the levels in the room or corridor (P < .01).These tests show that the unit can be used to create a mobile protective environment for immune-suppressed patients in a standard hospital setting.CONCLUSIONSThese tests show that the unit can be used to create a mobile protective environment for immune-suppressed patients in a standard hospital setting. |
| Author | Fischer, Alain Challier, Svetlana Malbernard, Mireille Bergeron, Vance Gangneux, Jean-Pierre Poirot, Jean-Louis Laudinet, Nicolas |
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| CitedBy_id | crossref_primary_10_1016_j_jhin_2022_06_013 crossref_primary_10_1016_S1773_035X_08_73334_3 crossref_primary_10_1016_j_ajic_2009_09_014 crossref_primary_10_1016_j_buildenv_2020_106643 crossref_primary_10_1016_j_ajic_2008_12_006 crossref_primary_10_1017_ice_2016_81 crossref_primary_10_1016_j_jhin_2022_02_002 crossref_primary_10_1016_j_jhin_2025_02_015 crossref_primary_10_3109_13693786_2011_575890 crossref_primary_10_1016_j_jhin_2010_08_012 crossref_primary_10_1007_s12553_020_00480_z crossref_primary_10_1016_j_jhin_2008_03_018 crossref_primary_10_1016_j_jopr_2013_01_013 crossref_primary_10_1017_ice_2017_18 |
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| Snippet | Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats... Background Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne... BACKGROUND: Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne... |
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| SubjectTerms | Air Microbiology Air Pollution, Indoor Air Pollution, Indoor - prevention & control Aspergillosis Aspergillosis - microbiology Aspergillosis - prevention & control Aspergillus Aspergillus - isolation & purification Child Child, Preschool Colony Count, Microbial Decontamination Decontamination - instrumentation Environment, Controlled Equipment Design France Fungi Fungi - isolation & purification Hospitals, Pediatric Humans Immunocompromised Host Infection Control Infection Control - instrumentation Infectious Disease Life Sciences Microbiology and Parasitology Mycoses Mycoses - prevention & control |
| Title | Evaluation of a new mobile system for protecting immune-suppressed patients against airborne contamination |
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