Long-term follow-up of neonatal mitochondrial cytopathies: a study of 57 patients

• Published in: Pediatrics (Evanston) Vol. 116; no. 5; p. 1170
• Main Authors: García-Cazorla, A, De Lonlay, P, Nassogne, M C, Rustin, P, Touati, G, Saudubray, J M
• Format: Journal Article
• Language: English
• Published: United States 01.11.2005
• Subjects: Child, Preschool; Disease Progression; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases - blood; Infant, Newborn, Diseases - diagnosis; Infant, Newborn, Diseases - mortality; Lactic Acid - blood; Male; Mitochondrial Myopathies - blood; Mitochondrial Myopathies - complications; Mitochondrial Myopathies - diagnosis; Mitochondrial Myopathies - mortality; Prognosis

We sought to determine the long-term clinical and biochemical outcome of newborns with mitochondrial cytopathies (MCs) and to identify possible prognostic factors that may modify the course of these diseases. Fifty-seven newborns with MCs were identified in a retrospective review (1983-2002). We def...