Comparison of the induction of neutralizing antibodies against Bas congo virus using several vaccine modalities

• Published in: Scientific reports Vol. 15; no. 1; pp. 16285 - 11
• Main Authors: Park, Eun-Sil, Yoshikawa, Tomoki, Tani, Hideki, Kimura, Masanobu, Kaku, Yoshihiro, Imaoka, Koichi, Maeda, Ken, Saijo, Masayuki, Morikawa, Shigeru
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 10.05.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 631/250/590; 692/699/255; Animals; Antibodies; Antibodies, Neutralizing - immunology; Antibodies, Viral - immunology; Epidemics; Fever; Hemorrhagic fever; Humanities and Social Sciences; Hydrogen peroxide; Immunization; Infections; Infectious diseases; Inoculation; Laboratory animals; multidisciplinary; Pathogens; Plant viruses; Proteins; Rabbits; Science; Science (multidisciplinary); Serology; Stomatitis; Vaccines; Vaccinia virus - genetics; Vaccinia virus - immunology; Veterinary medicine; Viral Envelope Proteins - genetics; Viral Envelope Proteins - immunology; Viral Vaccines - immunology; Virology

The Bas-Congo virus (BASV) is a novel rhabdovirus that causes viral hemorrhagic fever in 2009. Since BASV has not been isolated, there is limited information on BASV, and potential therapeutics or vaccines have not yet been developed. In the present study, we used the synthetic cDNA of the BASV-G pr...