Identification of autophagy-related immune targets for enhancing immunotherapy in pancreatic cancer aggressiveness

• Published in: Discover. Oncology Vol. 16; no. 1; pp. 382 - 17
• Main Authors: Deng, Qianxi, Wu, Linju, He, Jin, Wu, Fan, Jiang, Zheng
• Format: Journal Article
• Language: English
• Published: New York Springer US 24.03.2025; Springer Nature B.V; Springer
• Subjects: Antibodies; Autophagy; Autophagy-related genes; Cancer Research; Cancer therapies; Genes; Immune infiltration; Immune system; Immunotherapy; Internal Medicine; Medical prognosis; Medicine; Medicine & Public Health; Metastasis; MicroRNAs; Molecular Medicine; Oncology; Pancreatic cancer; Prognostic model; Radiotherapy; RHEB; Surgical Oncology; China; Prognostic model; Autophagy-related genes; Metastasis; RHEB; Pancreatic cancer; Immune infiltration

Background Pancreatic cancer (PC) presents significant challenges in oncology, with metastasis critically affecting patient outcomes. Autophagy-related genes (ARGs)’s involvement in influencing immune activity and metastasis in PC remains inadequately understood. Aim This study seeks to identify and...