Group comparison of cortical fiber connectivity map: An application between post-stroke patients and healthy subjects

• Published in: Neuroscience Vol. 344; pp. 15 - 24
• Main Authors: Liu, Kai, Zhang, Teng, Chu, Winnie C.W., Mok, Vincent C.T., Wang, Defeng, Shi, Lin
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 06.03.2017
• Subjects: Aged; Brain - diagnostic imaging; Connectome; cortex; Feasibility Studies; Female; fiber connectivity map; Humans; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Neural Pathways - diagnostic imaging; Neurology; Reproducibility of Results; Severity of Illness Index; Stroke - diagnostic imaging; vertex-wise statistical analysis; vertex-wise statistical analysis; FFE; GLM; MNI; T1WI; dMRI; SC; MMSE; WM; FLAIR; connectome; VBM; cortex; FiCD; FCD; TBSS; fiber connectivity map; AFs; NINDS; 3D; CU; IIT; FWHM; Qdec; VLSM; FA; TIR; fast field echo; association fibers; functional connectivity density; General Linear Model; three-dimensional; tract-based spatial statistics; Illinois Institute of Technology; T1-weighted image; Fluid attenuation inversion recovery; fiber connectivity density; diffusion magnetic resonance imaging; white matter; structural connectivity; vertex-based morphometry; Mini-Mental Screening Examination; Query Design Estimate Contrast; cortical unit; turbo inversion recovery; Montreal Neurological Institute; vertex-based lesion-symptom mapping; fractional anisotropy; Neurological Disorders and Stroke; Full Width at Half Maximum

•This study showed the feasibility of applying group comparison vertex-wise analysis for cortical structural connectivity.•A fiber connectivity density (FiCD) method based on connectome method was applied to measure whole-brain FiCD map.•Stroke and healthy participants were enrolled for the FiCD mea...