GIFT4 fusokine converts leukemic B cells into immune helper cells - Deng, Jiusheng; Pennati, Andrea; Cohen, Jonathon B.; Wu, Yuanqiang; Ng, Spencer; Wu, Jian Hui; Flowers, Christopher R.; Galipeau, Jacques (Journal of translational medicine, 2016)
Keywords: Adult; Aged; Animals; Antigen-Presenting Cells - drug effects; Antigen-Presenting Cells - metabolism; B cells; Care and treatment; Cell Proliferation - drug effects; Cross-Priming - drug effects; Cytokines; Cytotoxicity, Immunologic - drug effects; Diagnosis; Female; Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology; Humans; Immunotherapy; Interleukin-4 - pharmacology; Janus Kinases - metabolism; Leukemia, Lymphocytic, Chronic, B-Cell - immunology; Leukemia, Lymphocytic, Chronic, B-Cell - pathology; Lymphocytic leukemia; Male; Mice; Middle Aged; Phenotype; Proteome - secretion; Recombinant Fusion Proteins - pharmacology; Signal Transduction - drug effects; STAT5 Transcription Factor - metabolism; T cells; T-Lymphocytes, Helper-Inducer - cytology; T-Lymphocytes, Helper-Inducer - drug effects; T-Lymphocytes, Helper-Inducer - immunology; Chronic lymphocytic leukemia; T cells; Immunotherapy; GIFT4 fusokine