Tagging single nucleotide polymorphisms in the PPAR-γ and RXR-α gene and type 2 diabetes risk：a case-control study of a Chinese Han population

• Published in: Journal of biomedical research Vol. 25; no. 1; pp. 33 - 41
• Main Authors: Du, Juan, Shi, Hui, Lu, Ying, Du, Wencong, Cao, Yuanyuan, Li, Qian, Ma, Jianhua, Ye, Xinhua, Cheng, Jinluo, Yu, Xiaofang, Gao, Yanqin, Zhou, Ling
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.01.2011; Editorial Department of Journal of Biomedical Research
• Subjects: 2型糖尿病; peroxisome proliferators-activated receptor-γ; PPAR; Research Paper; retinoid X receptor-α; serum adiponectin; single nucleotide polymorphism; type 2 diabetes mellitus; 中国汉族人群; 单核苷酸; 多态性标记; 等位基因频率; 过氧化物酶体增殖物激活受体; peroxisome proliferators-activated receptor-γ; type 2 diabetes mellitus; serum adiponectin; single nucleotide polymorphism; retinoid X receptor-α

Peroxisome proliferator-activated receptor （PPAR-γ）,which is mainly involved in adipocyte differentiation, has been suggested to play an important role in the pathogenesis of insulin resistance and atherosclerosis. We investigated the frequencies of two common tagging polymorphisms of the PPAR-γ gen...