Assessment of the Urinary Microbiota of MSM Using Urine Culturomics Reveals a Diverse Microbial Environment

• Published in: Clinical chemistry (Baltimore, Md.) Vol. 68; no. 1; pp. 192 - 203
• Main Authors: Sawhney, Sanjam S, Johnson, Caitlin, Shupe, Angela, Fine, Jeremy, Dantas, Gautam, Burnham, Carey-Ann D, Yarbrough, Melanie L
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.01.2022
• Subjects: Anaerobic microorganisms; Anal intercourse; Antibiotics; Composition; Culture; Demographics; Demography; Gay couples; Gene sequencing; Health aspects; HIV; Homosexuality, Male; Human immunodeficiency virus; Humans; Male; Mass spectrometry; Mass spectroscopy; Microbial activity; Microbiota; Microbiota (Symbiotic organisms); Microorganisms; Mucosa; Risk analysis; Risk factors; RNA, Ribosomal, 16S - genetics; rRNA 16S; Sexual and Gender Minorities; Sexually transmitted diseases; Species; Species diversity; STD; Urinary tract; Urinary Tract Infections - diagnosis; Urine; United States; urinary microbiota; MSM; enhanced urine culture

Abstract Background The urinary tract is not sterile and is populated by microbial communities that influence urinary health. Men who have sex with men (MSM) are understudied yet have increased risk factors for genitourinary infections. Our objective was to interrogate the composition of MSM urinary...