Malabaricone C isolated from edible plants as a potential inhibitor of SARS-CoV-2 infection

• Published in: Scientific reports Vol. 15; no. 1; pp. 8518 - 10
• Main Authors: Mutmainah, Murai, Yuta, Fujimoto, Ai, Kawamura, Rintaro, Kitamura, Akira, Koolath, Sajeer, Usuki, Seigo, Sasaki, Michihito, Orba, Yasuko, Igarashi, Yasuyuki, Sawa, Hirofumi, Sato, Akihiko, Monde, Kenji
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 12.03.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 631/92/287; 631/92/349; 692/4017; Animals; Antiviral Agents - chemistry; Antiviral Agents - isolation & purification; Antiviral Agents - pharmacology; Cell fusion; Chlorocebus aethiops; Coronaviruses; COVID-19; COVID-19 - virology; COVID-19 Drug Treatment; Global health; HEK293 Cells; Humanities and Social Sciences; Humans; Mammalian cells; multidisciplinary; Natural & organic foods; Nucleotide analogs; Plants, Edible - chemistry; Public health; SARS-CoV-2 - drug effects; Science; Science (multidisciplinary); Severe acute respiratory syndrome coronavirus 2; Sphingomyelin; Vero Cells; Viral infections; Virus Internalization - drug effects

Although the SARS-CoV-2 epidemic worldwide has gradually decreased, in some areas, the situation has not yet been stamped and has become a global health emergency. It is quite possible that we could again be threatened by a new coronavirus. Therefore, new nucleotide analog drugs and vaccines or usin...