Identifying propionate metabolism-related genes as biomarkers of sepsis development and therapeutic targets - Yang, Lechen; Shang, Weifeng; Chen, Dongjie; Qian, Hang; Zhang, Sheng; Pan, Xiaojun; Huang, Sisi; Liu, Jiao; Chen, Dechang (Scientific reports, 2025)
Keywords: 631/250; 692/308/2056; Abdomen; Algorithms; Archives & records; Bcl-6 protein; Biomarkers - metabolism; Bone morphogenetic protein receptor type II; CDX2 protein; Cell differentiation; Cell interactions; Communication; Datasets; Diagnostic modeling; FOXO4 protein; Gene expression; Gene Expression Profiling; Gene Regulatory Networks; Humanities and Social Sciences; Humans; Interferon regulatory factor 4; Intestinal microflora; Laboratory animals; Leukocytes (mononuclear); Leukocytes (neutrophilic); Leukocytes, Mononuclear - metabolism; Lymphocytes B; Machine learning; Male; Metabolism; Microbiota; multidisciplinary; Pathophysiology; Performance evaluation; Peripheral blood mononuclear cells; Plasma cells; Propionate metabolism; Propionates - metabolism; Propionic acid; Science; Science (multidisciplinary); Sepsis; Sepsis - diagnosis; Sepsis - genetics; Sepsis - metabolism; Single-Cell Analysis; Software; Statistical analysis; Therapeutic targets; Transcription Factors - genetics; Transcription Factors - metabolism; Wound healing; Propionate metabolism; Plasma cells; Sepsis; Diagnostic modeling; Machine learning