Gut microbiota influences low fermentable substrate diet efficacy in children with irritable bowel syndrome

• Published in: Gut microbes Vol. 5; no. 2; pp. 165 - 175
• Main Authors: Chumpitazi, Bruno P, Hollister, Emily B, Oezguen, Numan, Tsai, Cynthia M, McMeans, Ann R, Luna, Ruth A, Savidge, Tor C, Versalovic, James, Shulman, Robert J
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.03.2014; Landes Bioscience
• Subjects: abdominal pain; Abdominal Pain - diet therapy; Abdominal Pain - microbiology; Adolescent; Child; Diet; Feces - microbiology; Female; Fermentation; FODMAPs; Gastrointestinal Tract - microbiology; Humans; Hydrogen - metabolism; irritable bowel syndrome; Irritable Bowel Syndrome - diet therapy; Irritable Bowel Syndrome - microbiology; Male; metabolites; Methane - metabolism; microbiome; pediatric; Pilot Projects; Research Paper; abdominal pain; irritable bowel syndrome; metabolites; microbiome; FODMAPs; pediatric

We sought to determine whether a low fermentable substrate diet (LFSD) decreases abdominal pain frequency in children with irritable bowel syndrome (IBS) and to identify potential microbial factors related to diet efficacy. Pain symptoms, stooling characteristics, breath hydrogen and methane, whole...