Genotype B3.13 influenza A(H5N1) viruses isolated from dairy cattle demonstrate high virulence in laboratory models, but retain avian virus-like properties - Fabrizio, Thomas P.; Kandeil, Ahmed; Harrington, Walter N.; Jones, Jeremy C.; Jeevan, Trushar; Andreev, Konstantin; Seiler, Patrick; Fogo, Jonathan; Davis, Morgan L.; Crumpton, Jeri Carol; Franks, John; DeBeauchamp, Jennifer; et al. (Nature communications, 2025)
Keywords: 13/106; 13/51; 14/63; 45/23; 45/88; 631/326/596/1578; 631/326/596/2555; 631/326/596/2563; 64/60; Animals; Antiviral agents; Antiviral Agents - pharmacology; Avian flu; Birds - virology; Cattle; Cow's milk; Dairy cattle; Disease Models, Animal; Epithelial cells; Epithelium; Fatalities; Female; Ferrets - virology; Genotype; Genotype & phenotype; Genotypes; Glycosylation; Humanities and Social Sciences; Humans; Influenza; Influenza A; Influenza A Virus, H5N1 Subtype - drug effects; Influenza A Virus, H5N1 Subtype - genetics; Influenza A Virus, H5N1 Subtype - isolation & purification; Influenza A Virus, H5N1 Subtype - pathogenicity; Influenza in Birds - virology; Influenza, Human - transmission; Influenza, Human - virology; Laboratory animals; Mice; Milk; Milk - virology; Mortality; multidisciplinary; Mustela; Orthomyxoviridae Infections - transmission; Orthomyxoviridae Infections - virology; Pathogenesis; Poultry; Preferences; Science; Science (multidisciplinary); Vaccines; Vigilance; Virulence; Virulence - genetics; Virus Replication; Viruses; Zoonoses; Louisiana; Ghana; Ohio; California; United States--US; Texas