The potential effect of gut microbiota on the secretion of selected cytokines by human cells in vitro

• Published in: Scientific reports Vol. 15; no. 1; pp. 17367 - 8
• Main Authors: Kopa-Stojak, Paulina Natalia, Kleniewska, Paulina, Hoffmann, Arkadiusz, Pawliczak, Rafał
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 19.05.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 631/250; 692/308; 692/420; Airway inflammation; Asthma; Asthma - immunology; Asthma - microbiology; Cytokines; Cytokines - metabolism; Digestive system; Enzymes; Gastrointestinal Microbiome; Gastrointestinal tract; Gut microbiota; HT29 Cells; Humanities and Social Sciences; Humans; Immune system; Immunoassays; Interleukin 13; Interleukin 5; Interleukin 8; Interleukin-13 - metabolism; Interleukin-8 - metabolism; Intestinal microflora; Leukocytes (mononuclear); Leukocytes, Mononuclear - immunology; Leukocytes, Mononuclear - metabolism; Lysates; Microbiota; Monocytes; Monocytes - immunology; Monocytes - metabolism; multidisciplinary; Peripheral blood mononuclear cells; Science; Science (multidisciplinary); Airway inflammation; Intestinal microflora; Asthma

Colonization of the gut early in life plays a significant role in guiding the development of the immune system. The effect of individual intestinal bacterial strains on the asthma development is the subject of numerous scientific studies. The aim of the study was to determine the role and the potent...