Pilot study of atomoxetine in patients with Parkinson's disease and dopa-unresponsive Freezing of Gait

• Published in: Translational neurodegeneration Vol. 4; no. 1; p. 24
• Main Authors: Revuelta, Gonzalo J, Embry, Aaron, Elm, Jordan J, Gregory, Chris, Delambo, Amy, Kautz, Steve, Hinson, Vanessa K
• Format: Journal Article
• Language: English
• Published: England BioMed Central 10.12.2015
• Subjects: Short Report; Freezing of gait; Atomoxetine; Noradrenaline; Parkinson’s disease; Dopa-response

Freezing of gait (FoG) is a common and debilitating condition in Parkinson's disease (PD) associated with executive dysfunction. A subtype of FoG does not respond to dopaminergic therapy and may be related to noradrenergic deficiency. This pilot study explores the effects of atomoxetine on gait...