Periostin mediates collagen production, ECM remodeling and myofibroblast differentiation in breast prosthesis capsule formation - Yang, Ying; Li, Shumo; Bian, Li; Dai, Xiaoming; Hu, Jun; Ma, Yun; Wang, Zhiyuan (Scientific reports, 2025)
Keywords: 692/4028; 692/420; 692/699; Animal models; Animals; Antibodies; Bacterial infections; Breast; Breast implants; Breast Implants - adverse effects; Capsular contraction; Cell Adhesion Molecules - genetics; Cell Adhesion Molecules - metabolism; Cell Differentiation; Cell Proliferation; Collagen; Collagen - biosynthesis; Collagen - metabolism; Cross-linking; Cytokines; Enzymes; Extracellular matrix; Extracellular Matrix - metabolism; Female; Fibroblasts; Fibroblasts - metabolism; Fibronectin; Fibrosis; Humanities and Social Sciences; Humans; Implant Capsular Contracture - metabolism; Implant Capsular Contracture - pathology; Inflammation; Lysyl oxidase; Matrix protein; Mice; mRNA; multidisciplinary; Myofibroblasts - cytology; Myofibroblasts - metabolism; Periostin; Physiology; Polymerase chain reaction; Prostheses; Protein-Lysine 6-Oxidase - genetics; Protein-Lysine 6-Oxidase - metabolism; Proteins; Reconstructive surgery; Science; Science (multidisciplinary); Silicon implant; Silicones; Surgery; Tenascin; Tenascin C; Therapeutic targets; Transforming growth factor-b; United States--US; Guangzhou China; China; Fibroblasts; Capsular contraction; Animals; Breast implants/Adverse effects; Silicon implant; Periostin