Capillary electrophoresis–electrospray ionization-mass spectrometry interfaces: Fundamental concepts and technical developments

• Published in: Journal of Chromatography A Vol. 1267; pp. 17 - 31
• Main Authors: Bonvin, Grégoire, Schappler, Julie, Rudaz, Serge
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 07.12.2012
• Subjects: Capillary electrophoresis; CE–ESI-MS interfaces; chromatography; electrochemistry; Electrophoresis, Capillary - instrumentation; Electrophoresis, Capillary - methods; ionization; ions; Mass spectrometry; Spectrometry, Mass, Electrospray Ionization - instrumentation; Spectrometry, Mass, Electrospray Ionization - methods; CE–ESI-MS interfaces; Capillary electrophoresis; Mass spectrometry

▸ The ESI process is deeply explained in the context of CE. ▸ The electrochemical processes involved in CE–ESI-MS are presented. ▸ CE–ESI-MS interfaces are classified based on their operating flow rates. ▸ Electrospray and nanospray interfaces and their applications are overviewed. Capillary electro...