Cell division cycle protein 42-driven activation of the MKK3/6-p38 signaling pathway participates in cardiac remodeling in mice - Wen, Ke; Xie, Lin; Liu, Quan-Wen; Yu, Guan-Hui; Qiao, Xu-Hui; Huang, Yu-Chun; Wang, Lu; Li, Xin; Wen, Li-Dan; Wang, Xiao-Lei; He, Jing; Xiao, Xin-Yu; et al. (Cellular and molecular life sciences : CMLS, 2025)
Keywords: Angiotensin II; Angiotensin II - pharmacology; Animal models; Animals; Aorta; Apoptosis; Biochemistry; Biomedical and Life Sciences; Biomedicine; Carbon dioxide; Cardiac function; Cardiomegaly - genetics; Cardiomegaly - metabolism; Cardiomegaly - pathology; Cardiomyocyte hypertrophy; Cardiomyocytes; cdc42 GTP-Binding Protein - antagonists & inhibitors; cdc42 GTP-Binding Protein - genetics; cdc42 GTP-Binding Protein - metabolism; Cdc42 protein; Cell Biology; Cell cycle; Cell division; Coronary vessels; Cycle protein; Cytoskeleton; Deletion; Fibrosis; Gene expression; Heart; Hypertrophy; Inflammation; Inhibitors; Kinases; Laboratory animals; Life Sciences; Male; MAP Kinase Kinase 3 - metabolism; MAP Kinase Kinase 6 - metabolism; MAP Kinase Signaling System; Membrane trafficking; Membranes; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocardium - metabolism; Myocardium - pathology; Myocytes; Myocytes, Cardiac - metabolism; Myocytes, Cardiac - pathology; Original; Original Article; p38 Mitogen-Activated Protein Kinases - metabolism; Penicillin; Polarization; Proteins; Rats; Signal Transduction; Thymus gland; Ventricular Remodeling; United States--US; Cardiomyocyte hypertrophy; Inflammation; Cardiac function; Apoptosis