Persistent SARS-CoV-2 infection: significance and implications

• Published in: The Lancet infectious diseases Vol. 24; no. 7; pp. e453 - e462
• Main Authors: Machkovech, Heather M, Hahn, Anne M, Garonzik Wang, Jacqueline, Grubaugh, Nathan D, Halfmann, Peter J, Johnson, Marc C, Lemieux, Jacob E, O'Connor, David H, Piantadosi, Anne, Wei, Wanting, Friedrich, Thomas C
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.07.2024; Elsevier Limited
• Subjects: Antigens; Asymptomatic; Case reports; Cohort analysis; COVID-19; COVID-19 vaccines; Disease transmission; Health services; HIV; Human immunodeficiency virus; Immune response; Infections; Persistent infection; Population levels; Public health; Replication; Risk factors; Severe acute respiratory syndrome coronavirus 2; Transplants & implants; Viral diseases; Viruses

SARS-CoV-2 causes persistent infections in a subset of individuals, which is a major clinical and public health problem that should be prioritised for further investigation for several reasons. First, persistent SARS-CoV-2 infection often goes unrecognised, and therefore might affect a substantial n...