Dental biofilms contain DNase I-resistant Z-DNA and G-quadruplexes but alternative DNase overcomes this resistance - Evans, Dominique C. S.; Kristensen, Mathilde F.; Minero, Gabriel Antonio S.; Palmén, Lorena G.; Knap, Inge; Tiwari, Manish K.; Schlafer, Sebastian; Meyer, Rikke L. (NPJ biofilms and microbiomes, 2025)
Keywords: 631/326/41; 631/326/46; 692/700/3032/3039/3049; Antibodies; Bacteria; Biofilms; Biofilms - drug effects; Biofilms - growth & development; Biomedical and Life Sciences; Cell surface; Chloroquine; Confocal microscopy; Conformation; Dental caries; Dental Caries - microbiology; Deoxyribonuclease; Deoxyribonuclease I - metabolism; DNA structure; DNA, Bacterial - chemistry; Environmental DNA; Enzymes; G-Quadruplexes; Humans; Life Sciences; Medical Microbiology; Microbial Ecology; Microbial Genetics and Genomics; Microbiology; Microorganisms; Microscopy; Microscopy, Confocal; Oral hygiene; Streptococcus mutans - drug effects; Streptococcus mutans - genetics; Streptococcus mutans - physiology; Z-form