Impact of temporal tear meniscus height on the tear osmolarity measurements

• Published in: Scientific reports Vol. 15; no. 1; pp. 27459 - 10
• Main Authors: Lee, Jaekyoung, Bang, Seung Pil, Kim, Jae-Gon, Jun, Jong Hwa
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 28.07.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 692/53/2421; 692/699/3161/3163; Adult; Aged; Clinical medicine; Disease; Dry eye; Dry Eye Syndromes - diagnosis; Dry Eye Syndromes - metabolism; Eye; Eye diseases; Female; Gelatinase B; Humanities and Social Sciences; Humans; Inflammation; Male; Matrix metalloproteinase; Matrix Metalloproteinase 9 - metabolism; Meniscus; Metalloproteinase; Middle Aged; multidisciplinary; Osmolar Concentration; Osmolarity; Osmotic pressure; Prospective Studies; Science; Science (multidisciplinary); Sjogren's syndrome; Sjogren's Syndrome - diagnosis; Sjogren's Syndrome - metabolism; Tear meniscus height; Tear meniscus osmolarity; TearLab; Tears; Tears - chemistry; Tears - metabolism; Tumor necrosis factor-TNF; United States > US; Tear meniscus osmolarity; Tear meniscus height; TearLab; Dry eye

Tear hyperosmolarity plays a crucial role in initiation of inflammatory response and damage to ocular surface epithelia. Accurate measurement of tear osmolarity is essential for dry eye. This prospective observational and experimental study was conducted in 182 eyes of 182 participants, including 11...