Social isolation-induced increase in NMDA receptors in the hippocampus exacerbates emotional dysregulation in mice - Chang, Chih-Hua; Hsiao, Ya-Hsin; Chen, Yu-Wen; Yu, Yang-Jung; Gean, Po-Wu (Hippocampus, 2015)
Keywords: acute stress; Affective Symptoms - etiology; Affective Symptoms - pathology; aggression; Aggression - physiology; Animals; Animals, Newborn; depression; Dizocilpine Maleate - pharmacology; Excitatory Amino Acid Antagonists - pharmacology; Excitatory Postsynaptic Potentials - drug effects; Exploratory Behavior - physiology; Gene Expression Regulation - physiology; Hippocampus - cytology; Hippocampus - metabolism; Male; Membrane Potentials - drug effects; Membrane Potentials - physiology; Mice; Mice, Inbred C57BL; Neurons - drug effects; Neurons - physiology; NMDA receptor; Piperidines - pharmacology; Prepulse Inhibition - drug effects; Prepulse Inhibition - physiology; Random Allocation; Receptors, N-Methyl-D-Aspartate - metabolism; Reflex, Startle - physiology; social isolation; Social Isolation - psychology; Swimming - psychology; Synaptosomes - drug effects; Synaptosomes - metabolism; social isolation; aggression; depression; NMDA receptor; acute stress