Different prognostic roles of tumor suppressor gene BAP1 in cancer: A systematic review with meta-analysis

• Published in: Genes chromosomes & cancer Vol. 55; no. 10; pp. 741 - 749
• Main Authors: Luchini, Claudio, Veronese, Nicola, Yachida, Shinichi, Cheng, Liang, Nottegar, Alessia, Stubbs, Brendon, Solmi, Marco, Capelli, Paola, Pea, Antonio, Barbareschi, Mattia, Fassan, Matteo, Wood, Laura D, Scarpa, Aldo
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.10.2016; Wiley Subscription Services, Inc
• Subjects: Female; Genes, Tumor Suppressor; Humans; Male; Mutation; Neoplasm Recurrence, Local - genetics; Neoplasm Recurrence, Local - mortality; Neoplasms - genetics; Neoplasms - mortality; Prognosis; PubMed; Risk Factors; Tumor Suppressor Proteins - genetics; Ubiquitin Thiolesterase - genetics

Biallelic inactivation of the tumor suppressor gene BRCA1‐associated protein 1 (BAP1) has been demonstrated in several cancers, but its prognostic role has not been completely explained. We aimed to investigate the risk associated with loss of BAP1 (BAP1‐) for all‐cause mortality, cancer‐specific mo...