From Alcohol Toxicity to Treatment

• Published in: Alcoholism, clinical and experimental research Vol. 29; no. 7; pp. 1341 - 1350
• Main Authors: Seitz, Helmut K., Salaspuro, Mikko, Savolainen, Markku, Haber, Paul, Ishii, Hiromasa, Teschke, Rolf, Moshage, Hans, Lieber, Charles S.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.07.2005; Lippincott Williams & Wilkins
• Subjects: Acetaldehyde - metabolism; Acetaldehyde - toxicity; Alcohol Dehydrogenase - genetics; Alcohol-Related Disorders - etiology; Alcohol-Related Disorders - genetics; Alcohol-Related Disorders - rehabilitation; Alcoholism - genetics; Alcoholism - rehabilitation; Alcoholism and acute alcohol poisoning; Alleles; Biological and medical sciences; Cholestasis, Intrahepatic - genetics; Cytochrome P-450 CYP2E1 - genetics; Dose-Response Relationship, Drug; Ethanol - toxicity; Genetic Predisposition to Disease - genetics; Genotype; Humans; Inactivation, Metabolic - genetics; Liver Diseases, Alcoholic - etiology; Liver Diseases, Alcoholic - genetics; Medical sciences; Neoplasms - genetics; Risk; Toxicology; Cytochrome; Toxicity; Transcriptome; Hepatic disease; Hepatocellular carcinoma; Biliary tract disease; Gastrointestinal; Microsome; Acetaldehyde; Hepatic Fibrogenesis; Alcoholic beverage; Hepatitis; Hepatic Transcriptome; Bacteria; Cytochrome P4502E1; Alcoholic Hepatitis; Annexin A2; Phosphatidylethanol; Stomach; Ethanol; Digestive system; Alcoholism; Gut; Gastrointestinal Bacteria; Malignant tumor; Treatment; Cholostasis; Metabolic activation; Digestive diseases; Microsomal Ethanol Oxidizing System; Cholestasis

This article presents the proceedings of a symposium held at the meeting of the International Society for Biomedical Research on Alcoholism in Mannheim, Germany, in October 2004. This symposium was dedicated to Charles S. Lieber in recognition of his contribution in alcohol research over the last 50...