Associations between metabolomic-identified changes of biomarkers and arterial stiffness in subjects progressing to impaired fasting glucose

• Published in: Clinical endocrinology (Oxford) Vol. 83; no. 2; pp. 196 - 204
• Main Authors: Jung, Saem, Kim, Minjoo, Lee, Young Ju, Lee, Sang-Hyun, Lee, Jong Ho
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.08.2015; Wiley Subscription Services, Inc
• Subjects: Adult; Age Factors; Aged; Ankle Brachial Index; Anthropometry; Antigens, CD - blood; Biomarkers - metabolism; Blood Flow Velocity; Blood Glucose - analysis; Blood Pressure; C-Reactive Protein - metabolism; Case-Control Studies; Diet; Fasting; Female; Homeostasis; Humans; Lactosylceramides - blood; Linear Models; Lipoproteins, LDL - analysis; Male; Malondialdehyde - blood; Metabolome; Middle Aged; Particle Size; Phosphatidylcholines - blood; Prospective Studies; Vascular Stiffness

Summary Objective We investigated correlations between age‐related changes in circulating metabolites and arterial stiffness in impaired fasting glucose (IFG). Design, subjects, measurement This prospective cohort study included 602 healthy, normal fasting glucose (NFG) subjects (30–65 years old) wh...