Infectious Diarrhea Due to Clostridium perfringens
In Clostridium perfringens food poisoning, an association between diarrhea and fecal enterotoxin is well established. Enterotoxin is found only in feces from symptomatic or infected persons and is absent from those of convalescent or healthy subjects. A rise in titer of antibody to the enterotoxin h...
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Published in | The Journal of infectious diseases Vol. 157; no. 2; pp. 390 - 391 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
United States
The University of Chicago Press
01.02.1988
University of Chicago Press |
Subjects | |
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Abstract | In Clostridium perfringens food poisoning, an association between diarrhea and fecal enterotoxin is well established. Enterotoxin is found only in feces from symptomatic or infected persons and is absent from those of convalescent or healthy subjects. A rise in titer of antibody to the enterotoxin has been documented, and administration of greater than or equal to 10 mg of purified enterotoxin to human volunteers produced diarrhea and abdominal pain. The authors have examined fecal specimens from cases of presumed infections diarrhea for the presence of bacterial exotoxins; earlier, they described the discovery of C. perfringens enterotoxin in 11 patients with presumed infectious diarrhea. This series has now been extended to 50 patients and confirms C. perfringens as a cause of infectious diarrhea unassociated with poisoning from food. |
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AbstractList | In Clostridium perfringens food poisoning, an association between diarrhea and fecal enterotoxin is well established. Enterotoxin is found only in feces from symptomatic or infected persons and is absent from those of convalescent or healthy subjects. A rise in titer of antibody to the enterotoxin has been documented, and administration of greater than or equal to 10 mg of purified enterotoxin to human volunteers produced diarrhea and abdominal pain. The authors have examined fecal specimens from cases of presumed infections diarrhea for the presence of bacterial exotoxins; earlier, they described the discovery of C. perfringens enterotoxin in 11 patients with presumed infectious diarrhea. This series has now been extended to 50 patients and confirms C. perfringens as a cause of infectious diarrhea unassociated with poisoning from food. |
Author | Borriello, S. Peter Larson, H. Elliott |
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Copyright | Copyright 1988 The University of Chicago |
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Notes | Please address requests for reprints to Dr. H. Elliott Larson, Microbial Pathogenicity Research Group, Division of Communicable Diseases, Clinical Research Centre, Watford Road, Harrow, Middlesex, England HA1 3UJ. ark:/67375/HXZ-6KWQTWV4-Q istex:F312F759794E464FCE7259DE10FBD8F9E9319104 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Correspondence-1 |
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SubjectTerms | Adult Aged Aged, 80 and over Antibodies Clostridium Infections Clostridium perfringens Correspondence Diarrhea Diarrhea - etiology Enterotoxins Feces Female Food poisoning Humans Infectious diseases Male Middle Aged Salmonella food poisoning Specimens Toxins |
Title | Infectious Diarrhea Due to Clostridium perfringens |
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