Cuscuta chinensis and C. campestris Attenuate Scopolamine-Induced Memory Deficit and Oxidative Damage in Mice

• Published in: Molecules (Basel, Switzerland) Vol. 23; no. 12; p. 3060
• Main Authors: Lin, Ming-Kuem, Lee, Meng-Shiou, Huang, Hui-Chi, Cheng, Tun-Jen, Cheng, Yih-Dih, Wu, Chi-Rei
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 22.11.2018; MDPI
• Subjects: Acetylcholinesterase - metabolism; Alzheimer's disease; Animals; Antioxidants; Avoidance Learning - drug effects; Brain; Brain - metabolism; Cuscuta - chemistry; Cuscuta campestris; Cuscuta chinensis; Cuscutae Semen; Drug dosages; Drugs, Chinese Herbal - administration & dosage; Drugs, Chinese Herbal - pharmacology; Enzymes; Flavonoids; Interleukin-1 - metabolism; Ischemia; Lipid Peroxidation - drug effects; Malondialdehyde - metabolism; Memory; Memory Disorders - chemically induced; Memory Disorders - drug therapy; Memory Disorders - metabolism; memory-improving properties; Mice; Neuropathology; Oxidation-Reduction - drug effects; Oxidative stress; Retention; scopolamine; Scopolamine - adverse effects; Traditional Chinese medicine; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-TNF; Cuscuta campestris; Cuscuta chinensis; Cuscutae Semen; memory-improving properties; scopolamine

The seeds of Cuscuta chinensis Lam. and C. campestris Yuncker have been commonly used as Chinese medical material for preventing aging. Our previous studies have found that C. chinensis and C. campestris possess anti-inflammatory activities in rodents. However, their other biological activities, suc...