Highly efficient local delivery of endothelial progenitor cells significantly potentiates angiogenesis and full-thickness wound healing

• Published in: Acta biomaterialia Vol. 69; pp. 156 - 169
• Main Authors: Wang, Chenggui, Wang, Qingqing, Gao, Wendong, Zhang, Zengjie, Lou, Yiting, Jin, Haiming, Chen, Xiaofeng, Lei, Bo, Xu, Huazi, Mao, Cong
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.03.2018; Elsevier BV
• Subjects: Angiogenesis; Appendages; Bioactive glass; Bioglass; Biological activity; Blood vessels; Cell growth; Cell-delivery nanocomposites; Cells; Cells (biology); Collagen; Endothelial progenitor cells; Granulation; Nanocomposites; Nanoparticles; Polycaprolactone; Progenitor cells; Regeneration (physiology); Regenerative medicine; SDF-1 protein; Skin; Stem cells; Therapy; Tissue engineering; Vascular endothelial growth factor; Vascularization; Wound healing; Bioactive glass; Angiogenesis; Wound healing; Cell-delivery nanocomposites; Endothelial progenitor cells

[Display omitted] Wound therapy with a rapid healing performance remains a critical clinical challenge. Cellular delivery is considered to be a promising approach to improve the efficiency of healing, yet problems such as compromised cell viability and functionality arise due to the inefficient deli...