The In Vitro Protective Role of Bovine Lactoferrin on Intestinal Epithelial Barrier

• Published in: Molecules (Basel, Switzerland) Vol. 24; no. 1; p. 148
• Main Authors: Zhao, Xiao, Xu, Xiao-Xi, Liu, Yang, Xi, En-Ze, An, Jing-Jing, Tabys, Dina, Liu, Ning
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 02.01.2019; MDPI
• Subjects: bovine lactoferrin; Cell cycle; Cell growth; Gene expression; human intestinal epithelial crypt cells; intestinal epithelial barrier; Pathogens; Permeability; Proteins; tight junction protein; Values; intestinal epithelial barrier; human intestinal epithelial crypt cells; tight junction protein; bovine lactoferrin; permeability

The intestinal epithelial barrier plays a key protective role in the gut lumen. Bovine lactoferrin (bLF) has been reported to improve the intestinal epithelial barrier function, but its impact on tight junction (TJ) proteins has been rarely described. Human intestinal epithelial crypt cells (HIECs)...