Evaluation of the Anti-Trypanosomal Activity of Vietnamese Essential Oils, with Emphasis on Curcuma longa L. and Its Components

• Published in: Molecules (Basel, Switzerland) Vol. 24; no. 6; p. 1158
• Main Authors: Le, Thanh Binh, Beaufay, Claire, Nghiem, Duc Trong, Pham, Tuan Anh, Mingeot-Leclercq, Marie-Paule, Quetin-Leclercq, Joëlle
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23.03.2019; MDPI
• Subjects: African trypanosomiasis; ar-curcumene; ar-turmerone, curlone; Chromatography; Curcuma longa; Curcuma zedoaria; Cytotoxicity; Essential oils; Gas chromatography; Ginger; Health risks; Litsea cubeba; Mammalian cells; Natural products; Oils & fats; Parasites; Selectivity; Trypanosoma; Trypanosoma brucei; Vector-borne diseases; Zingiber officinale; α-zingiberene, β-sesquiphellandrene; China; Curcuma zedoaria; Trypanosoma; Curcuma longa; Litsea cubeba; α-zingiberene, β-sesquiphellandrene; ar-turmerone, curlone; Zingiber officinale; ar-curcumene

Human African trypanosomiasis (HAT), known as sleeping sickness and caused by , is threatening low-income populations in sub-Saharan African countries with 61 million people at risk of infection. In order to discover new natural products against HAT, thirty-seven Vietnamese essential oils (EOs) were...