Neuroimmune Interactions and Rhythmic Regulation of Innate Lymphoid Cells

The Earth's rotation around its axis, is one of the parameters that never changed since life emerged. Therefore, most of the organisms from the cyanobacteria to humans have conserved natural oscillations to regulate their physiology. These daily oscillations define the circadian rhythms that se...

Full description

Saved in:
Bibliographic Details
Published inFrontiers in neuroscience Vol. 15; p. 657081
Main Authors Jacquelot, Nicolas, Belz, Gabrielle T, Seillet, Cyril
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Research Foundation 29.04.2021
Frontiers Media S.A
Subjects
Animal models
Asthma
Biological clocks
Catecholamines
Circadian rhythm
Circadian rhythms
Cytokines
Cytotoxicity
Diurnal variations
Food
Homeostasis
Hormones
Immune response
Inflammation
Lymphoid cells
Nervous system
neuroimmune interactions
neuropeptide
Neuropeptides
Neuroscience
Oscillations
Pathogens
Transcription factors
Viral infections
homeostasis
neuroimmune interactions
inflammation
neuropeptide
circadian rhythm
Online AccessGet full text

Cover

Abstract The Earth's rotation around its axis, is one of the parameters that never changed since life emerged. Therefore, most of the organisms from the cyanobacteria to humans have conserved natural oscillations to regulate their physiology. These daily oscillations define the circadian rhythms that set the biological clock for almost all physiological processes of an organism. They allow the organisms to anticipate and respond behaviorally and physiologically to changes imposed by the day/night cycle. As other physiological systems, the immune system is also regulated by circadian rhythms and while diurnal variation in host immune responses to lethal infection have been observed for many decades, the underlying mechanisms that affect immune function and health have only just started to emerge. These oscillations are generated by the central clock in our brain, but neuroendocrine signals allow the synchronization of the clocks in peripheral tissues. In this review, we discuss how the neuroimmune interactions create a rhythmic activity of the innate lymphoid cells. We highlight how the disruption of these rhythmic regulations of immune cells can disturb homeostasis and lead to the development of chronic inflammation in murine models.
AbstractList The Earth’s rotation around its axis, is one of the parameters that never changed since life emerged. Therefore, most of the organisms from the cyanobacteria to humans have conserved natural oscillations to regulate their physiology. These daily oscillations define the circadian rhythms that set the biological clock for almost all physiological processes of an organism. They allow the organisms to anticipate and respond behaviorally and physiologically to changes imposed by the day/night cycle. As other physiological systems, the immune system is also regulated by circadian rhythms and while diurnal variation in host immune responses to lethal infection have been observed for many decades, the underlying mechanisms that affect immune function and health have only just started to emerge. These oscillations are generated by the central clock in our brain, but neuroendocrine signals allow the synchronization of the clocks in peripheral tissues. In this review, we discuss how the neuroimmune interactions create a rhythmic activity of the innate lymphoid cells. We highlight how the disruption of these rhythmic regulations of immune cells can disturb homeostasis and lead to the development of chronic inflammation in murine models.
The Earth’s rotation around its axis, is one of the parameters that never changed since life emerged. Therefore, most of the organisms from the cyanobacteria to humans have conserved natural oscillations to regulate their physiology. These daily oscillations define the circadian rhythms that set the biological clock for almost all physiological processes of an organism. They allow the organisms to anticipate and respond behaviourally and physiologically to changes imposed by the day/night cycle. As other physiological systems, the immune system is also regulated by circadian rhythms and while diurnal variation in host immune responses to lethal infection have been observed for many decades, the underlying mechanisms that affect immune function and health have only just started to emerge. These oscillations are generated by the central clock in our brain, but neuroendocrine signals allow the synchronisation of the clocks in peripheral tissues. In this review, we discuss how the neuroimmune interactions create a rhythmic activity of the innate lymphoid cells. We highlight how the disruption of these rhythmic regulations of immune cells can disturb homeostasis and lead to the development of chronic inflammation in murine models.
Author Belz, Gabrielle T
Jacquelot, Nicolas
Seillet, Cyril
AuthorAffiliation 3 Diamantina Institute, The University of Queensland , Woolloongabba, QLD , Australia
1 Walter and Eliza Hall Institute of Medical Research , Parkville, VIC , Australia
2 Department of Medical Biology, University of Melbourne , Parkville, VIC , Australia
AuthorAffiliation_xml – name: 2 Department of Medical Biology, University of Melbourne , Parkville, VIC , Australia
– name: 1 Walter and Eliza Hall Institute of Medical Research , Parkville, VIC , Australia
– name: 3 Diamantina Institute, The University of Queensland , Woolloongabba, QLD , Australia
Author_xml – sequence: 1
  givenname: Nicolas
  surname: Jacquelot
  fullname: Jacquelot, Nicolas
  organization: Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia
– sequence: 2
  givenname: Gabrielle T
  surname: Belz
  fullname: Belz, Gabrielle T
  organization: Diamantina Institute, The University of Queensland, Woolloongabba, QLD, Australia
– sequence: 3
  givenname: Cyril
  surname: Seillet
  fullname: Seillet, Cyril
  organization: Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia
BackLink https://www.ncbi.nlm.nih.gov/pubmed/33994930$$D View this record in MEDLINE/PubMed
BookMark eNpdkUtrGzEUhUVJaB7tD-imDHTTjR09RhrNplBMmxhMAyGF7oQed2yZGcmVZgL-95Xj1DRdSeh-99yrc67QWYgBEPpA8Jwx2d50wYc8p5iSueANluQNuiRC0FnN2a-z072WF-gq5y3GgsqavkUXjLVt3TJ8iZY_YErRD8MUoFqGEZK2o48hVzq46mGzHzeDt9UDrKdeHwpV7AoX9AjVaj_sNtG7agF9n9-h8073Gd6_nNfo5_dvj4u72er-drn4uprZMnGcgXWtNUxKZwhuHKOOCWsa01CGHWsdUCqJ0bi2zugajGDctJI0ZV9HKaHsGi2Pui7qrdolP-i0V1F79fwQ01rpNHrbg3Kiw8IRA7TjNQNqnOwcry0mhHfcQtH6ctTaTWYAZyGMSfevRF9Xgt-odXxSkhDRclwEPr8IpPh7gjyqwWdb7NAB4pQV5cVxRjCVBf30H7qNUwrFqkKRlgtM66ZQ5EjZFHNO0J2WIVgdQlfPoatD6OoYeun5-O8vTh1_U2Z_AG5uq8c
CitedBy_id crossref_primary_10_3390_cancers14061578
crossref_primary_10_1146_annurev_nutr_062320_111321
crossref_primary_10_1016_j_tins_2022_06_006
crossref_primary_10_1016_j_trecan_2022_10_007
crossref_primary_10_3390_cancers13194806
crossref_primary_10_3390_ijms23042068
Cites_doi 10.1038/s41467-019-08427-3
10.1186/s40608-014-0033-1
10.1038/382250a0
10.1172/jci31021
10.1016/0889-1591(90)90033-m
10.1084/jem.20051615
10.1016/j.cell.2011.03.027
10.1507/endocrj.EJ12-0305
10.1038/nsmb.3018
10.1007/s12026-018-8989-4
10.1016/0192-0561(89)90187-2
10.1159/000481732
10.1093/jmcb/mjw012
10.1016/j.tem.2019.08.011
10.1210/jc.2002-021721
10.1038/s41423-019-0217-1
10.1046/j.1365-2249.2003.02190.x
10.1016/j.coi.2020.08.009
10.1016/s0006-291x(02)02462-2
10.1016/S0092-8674(03)01081-X
10.1016/j.immuni.2018.01.004
10.1016/j.cmet.2016.04.011
10.4049/jimmunol.1102715
10.1007/s11064-007-9501-z
10.1038/s41467-020-17197-2
10.1152/ajpendo.00057.2011
10.1038/nn1419
10.1084/jem.20190554
10.4049/jimmunol.1800484
10.1089/vim.1992.5.195
10.1016/s0165-5728(99)00271-4
10.1080/07420528.2019.1624373
10.1002/jcp.24273
10.1038/29795
10.1073/pnas.1408886111
10.1084/jem.20190549
10.1038/s41577-020-0397-z
10.1155/2020/9248479
10.1016/j.bbi.2005.10.002
10.1016/s0006-291x(02)02838-3
10.1002/cphy.c140003
10.1038/nature00965
10.1136/ard.62.7.593
10.4049/jimmunol.176.10.5958
10.1016/j.bbi.2010.08.007
10.1101/gad.873501
10.1111/j.1460-9568.2012.08213.x
10.1016/j.immuni.2014.10.007
10.1038/s41586-020-2039-9
10.4049/jimmunol.0902189
10.1016/0140-6736(90)93098-a
10.1155/2020/4176082
10.4049/jimmunol.174.12.7618
10.1093/sleep/30.4.401
10.7554/eLife.55388
10.4049/jimmunol.172.5.2811
10.1371/journal.pone.0187068
10.1038/ni.2002
10.1016/s0024-3205(01)01143-2
10.3390/cancers11040573
10.1038/s41590-019-0567-y
10.1210/jcem.83.5.4717
10.1111/j.1600-079x.1989.tb00663.x
10.1126/science.8160017
10.1016/0031-9384(87)90054-0
10.1016/j.psyneuen.2015.04.006
10.1210/jcem-60-6-1210
10.1371/journal.pone.0025079
10.1074/jbc.m116.743187
10.1152/ajpregu.00294.2004
10.1038/ni.2131
10.1210/jc.2018-00346
10.1126/science.289.5488.2344
10.1371/journal.pbio.1002269
10.1084/jem.20191054
10.1016/j.cmet.2015.06.005
10.1038/nature13823
10.1038/s41590-018-0185-0
10.1081/cbi-100103969
10.1016/s0960-9822(02)70684-2
10.1016/j.immuni.2007.01.011
10.1002/oby.21229
10.1073/pnas.0808180106
10.1038/ni.2045
10.1210/endo.142.6.8197
10.1155/2013/624123
10.1210/en.2009-0647
10.1016/j.neuron.2004.07.018
10.1016/0002-9343(88)90237-9
10.1016/j.cell.2018.07.017
10.1182/blood-2006-10-048215
10.1002/ijc.22248
10.1126/science.aan4829
10.1002/eji.201242382
10.1128/iai.00287-06
10.1084/jem.20121964
10.1016/j.mce.2014.10.018
10.1172/jci6762
10.1038/nature12526
ContentType Journal Article
Copyright Copyright © 2021 Jacquelot, Belz and Seillet.
2021. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright © 2021 Jacquelot, Belz and Seillet. 2021 Jacquelot, Belz and Seillet
Copyright_xml – notice: Copyright © 2021 Jacquelot, Belz and Seillet.
– notice: 2021. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: Copyright © 2021 Jacquelot, Belz and Seillet. 2021 Jacquelot, Belz and Seillet
DBID NPM
AAYXX
CITATION
3V.
7XB
88I
8FE
8FH
8FK
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
CCPQU
DWQXO
GNUQQ
HCIFZ
LK8
M2P
M7P
PIMPY
PQEST
PQQKQ
PQUKI
PRINS
Q9U
7X8
5PM
DOA
DOI 10.3389/fnins.2021.657081
DatabaseName PubMed
CrossRef
ProQuest Central (Corporate)
ProQuest Central (purchase pre-March 2016)
Science Database (Alumni Edition)
ProQuest SciTech Collection
ProQuest Natural Science Collection
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Natural Science Collection
ProQuest One Community College
ProQuest Central Korea
ProQuest Central Student
SciTech Premium Collection
Biological Sciences
Science Database
Biological Science Database
Publicly Available Content Database
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
ProQuest Central Basic
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle PubMed
CrossRef
Publicly Available Content Database
ProQuest Science Journals (Alumni Edition)
ProQuest Central Student
ProQuest Biological Science Collection
ProQuest Central Basic
ProQuest Central Essentials
ProQuest Science Journals
ProQuest One Academic Eastern Edition
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest Natural Science Collection
Biological Science Database
ProQuest SciTech Collection
ProQuest Central China
ProQuest Central
ProQuest One Academic UKI Edition
Natural Science Collection
ProQuest Central Korea
Biological Science Collection
ProQuest One Academic
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList CrossRef


Publicly Available Content Database
PubMed
Database_xml – sequence: 1
  dbid: DOA
  name: Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Anatomy & Physiology
EISSN 1662-453X
EndPage 657081
ExternalDocumentID oai_doaj_org_article_d6f06d1be2f543e2bd8fd54c0115f5ce
10_3389_fnins_2021_657081
33994930
Genre Journal Article
Review
GroupedDBID ---
29H
2WC
53G
5GY
5VS
88I
8FE
8FH
9T4
AAFWJ
ABUWG
ACGFO
ACGFS
ACXDI
ADRAZ
AEGXH
AENEX
AFKRA
AFPKN
AIAGR
ALMA_UNASSIGNED_HOLDINGS
AZQEC
BBNVY
BENPR
BHPHI
BPHCQ
C1A
CCPQU
CS3
DIK
DU5
DWQXO
E3Z
EBS
EJD
EMOBN
F5P
FRP
GNUQQ
GROUPED_DOAJ
GX1
HCIFZ
HYE
IAO
IEA
IHR
ISR
KQ8
LK8
M2P
M48
M7P
M~E
NPM
O5R
O5S
OK1
P2P
PGMZT
PIMPY
PQQKQ
PROAC
RNS
RPM
W2D
AAYXX
CITATION
3V.
7XB
8FK
PQEST
PQUKI
PRINS
Q9U
7X8
5PM
ID FETCH-LOGICAL-c493t-ecd9cb388db107d32d36cb7b7230d39de2281ba04cdba4eb635b9817949d22123
IEDL.DBID RPM
ISSN 1662-4548
1662-453X
IngestDate Tue Oct 22 15:03:46 EDT 2024
Tue Sep 17 20:58:36 EDT 2024
Fri Oct 25 04:45:13 EDT 2024
Thu Oct 10 17:05:16 EDT 2024
Fri Nov 22 00:24:11 EST 2024
Sat Sep 28 08:24:44 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Keywords homeostasis
neuroimmune interactions
inflammation
neuropeptide
circadian rhythm
Language English
License Copyright © 2021 Jacquelot, Belz and Seillet.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c493t-ecd9cb388db107d32d36cb7b7230d39de2281ba04cdba4eb635b9817949d22123
Notes ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Reviewed by: Stephen Beesley, Florida State University, United States; Tanja Lange, University of Lübeck, Germany; Brian James Altman, University of Rochester, United States
Edited by: Raghuveer Kavarthapu, National Institutes of Health (NIH), United States
This article was submitted to Neuroendocrine Science, a section of the journal Frontiers in Neuroscience
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116950/
PMID 33994930
PQID 2519560247
PQPubID 4424402
PageCount 1
ParticipantIDs doaj_primary_oai_doaj_org_article_d6f06d1be2f543e2bd8fd54c0115f5ce
pubmedcentral_primary_oai_pubmedcentral_nih_gov_8116950
proquest_miscellaneous_2528431028
proquest_journals_2519560247
crossref_primary_10_3389_fnins_2021_657081
pubmed_primary_33994930
PublicationCentury 2000
PublicationDate 2021-04-29
PublicationDateYYYYMMDD 2021-04-29
PublicationDate_xml – month: 04
  year: 2021
  text: 2021-04-29
  day: 29
PublicationDecade 2020
PublicationPlace Switzerland
PublicationPlace_xml – name: Switzerland
– name: Lausanne
PublicationTitle Frontiers in neuroscience
PublicationTitleAlternate Front Neurosci
PublicationYear 2021
Publisher Frontiers Research Foundation
Frontiers Media S.A
Publisher_xml – name: Frontiers Research Foundation
– name: Frontiers Media S.A
References Barnea (B12) 2015; 399
Hamnett (B33) 2019; 10
Seillet (B79); 21
Seshadri (B80) 2018; 201
Stern (B83) 2016; 23
Kim (B43) 2006; 176
De Boer (B20) 1987; 40
Wang (B93) 2021; 218
Arjona (B4) 2004; 172
Jahn (B36) 2015; 23
Talbot (B86) 2020; 579
Langendonk (B45) 1998; 83
O’Shea (B65) 2019; 11
Petty (B66) 1988; 85
Schiffer (B75) 2001; 18
Flier (B29) 2004; 116
Wang (B94) 2020; 20
Angeli (B2) 1988
Milano (B57) 1994; 264
Linsell (B49) 1985; 60
Dimitrov (B25) 2010; 184
Moriyama (B62) 2018; 359
Nussbaum (B63) 2013; 502
del Gobbo (B23) 1989; 11
Sun (B84) 2018; 17
Bahr (B10) 2018; 66
Sawa (B73) 2011; 12
Bodosi (B15) 2004; 287
Laue (B46) 2015; 2
Venneri (B90) 2018; 103
Luo (B54) 2016; 8
Yanofsky (B100) 2013; 2013
Ferno (B28) 2020; 31
Wen (B95) 2020; 2020
Brattsand (B16) 1996
Satoh-Takayama (B72) 2014; 41
Chang (B17) 2011; 12
McNulty (B55) 1990; 4
Messner (B56) 2001; 69
Fallon (B27) 2006; 203
Pickard (B67) 2014; 514
Kettner (B40) 2015; 22
Hashinaga (B34) 2013; 60
Logan (B51) 2011; 25
Kalsbeek (B38) 2001; 142
Molofsky (B59) 2013; 210
Seillet (B78) 2019; 16
Arjona (B5) 2005; 174
Ahima (B1) 1996; 382
Wieduwild (B96) 2020; 217
Kennaway (B39) 2019; 36
Gomez-Abellan (B32) 2010; 151
Lord (B53) 1998; 394
De Rosa (B22) 2007; 26
Scheer (B74) 2009; 106
Tian (B87) 2002; 298
Waite (B92) 2012; 36
Bennett (B13) 1996; 6
Todd (B88) 2020; 11
Logan (B52) 2012; 188
Spiga (B82) 2014; 4
Sanchez-Margalet (B70) 2003; 133
Monticelli (B60) 2011; 12
Kim (B42) 2007; 117
Zheng (B104) 2016; 291
Sato (B71) 2004; 43
De Lorenzo (B21) 2015; 57
Arjona (B7) 2008; 33
Azzari (B9) 1992; 5
Gnocchi (B31) 2017; 6
Tsang (B89) 2020; 9
Mori (B61) 2006; 119
Quatrini (B68) 2018; 19
Lamas (B44) 2013; 228
Xu (B99) 2015; 22
Arjona (B6) 2006; 20
Wilk (B97) 2013; 43
Arble (B3) 2011; 6
Surjit (B85) 2011; 145
Seillet (B77); 68
Zeng (B101) 2020; 2020
Olnes (B64) 2016; 6
Gavrila (B30) 2003; 88
Lewinski (B47) 1989; 7
Zhao (B103) 2003; 300
Jasinski-Bergner (B37) 2017; 10
Mitsui (B58) 2001; 15
Cutolo (B19) 2003; 62
Liu (B50) 2006; 74
Aton (B8) 2005; 8
Shimba (B81) 2018; 48
Vivier (B91) 2018; 174
Bhattacharyya (B14) 2007; 109
Reppert (B69) 2002; 418
Sears (B76) 1990; 336
Currier (B18) 2000; 104
Howard (B35) 1999; 104
Diaz-Salazar (B24) 2020; 217
Balsalobre (B11) 2000; 289
Dimitrov (B26) 2007; 30
Li (B48) 2015; 13
Keustermans (B41) 2017; 12
Wrann (B98) 2012; 302
Zhang (B102) 2014; 111
References_xml – volume: 10
  year: 2019
  ident: B33
  article-title: Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling.
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-019-08427-3
  contributor:
    fullname: Hamnett
– volume: 2
  year: 2015
  ident: B46
  article-title: Altered NK cell function in obese healthy humans.
  publication-title: BMC Obes
  doi: 10.1186/s40608-014-0033-1
  contributor:
    fullname: Laue
– volume: 382
  start-page: 250
  year: 1996
  ident: B1
  article-title: Role of leptin in the neuroendocrine response to fasting.
  publication-title: Nature
  doi: 10.1038/382250a0
  contributor:
    fullname: Ahima
– volume: 117
  start-page: 2621
  year: 2007
  ident: B42
  article-title: Obesity-associated improvements in metabolic profile through expansion of adipose tissue.
  publication-title: J. Clin. Invest.
  doi: 10.1172/jci31021
  contributor:
    fullname: Kim
– volume: 4
  start-page: 292
  year: 1990
  ident: B55
  article-title: Circadian analysis of mononuclear cells in the rat following pinealectomy and superior cervical ganglionectomy.
  publication-title: Brain Behav. Immun.
  doi: 10.1016/0889-1591(90)90033-m
  contributor:
    fullname: McNulty
– volume: 203
  start-page: 1105
  year: 2006
  ident: B27
  article-title: Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion.
  publication-title: J. Exp. Med.
  doi: 10.1084/jem.20051615
  contributor:
    fullname: Fallon
– volume: 145
  start-page: 224
  year: 2011
  ident: B85
  article-title: Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor.
  publication-title: Cell
  doi: 10.1016/j.cell.2011.03.027
  contributor:
    fullname: Surjit
– volume: 60
  start-page: 483
  year: 2013
  ident: B34
  article-title: Modulation by adiponectin of circadian clock rhythmicity in model mice for metabolic syndrome.
  publication-title: Endocr. J.
  doi: 10.1507/endocrj.EJ12-0305
  contributor:
    fullname: Hashinaga
– volume: 22
  start-page: 476
  year: 2015
  ident: B99
  article-title: Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus.
  publication-title: Nat. Struct. Mol. Biol.
  doi: 10.1038/nsmb.3018
  contributor:
    fullname: Xu
– volume: 66
  start-page: 234
  year: 2018
  ident: B10
  article-title: Impaired natural killer cell subset phenotypes in human obesity.
  publication-title: Immunol. Res.
  doi: 10.1007/s12026-018-8989-4
  contributor:
    fullname: Bahr
– volume: 11
  start-page: 567
  year: 1989
  ident: B23
  article-title: Pinealectomy inhibits interleukin-2 production and natural killer activity in mice.
  publication-title: Int. J. Immunopharmacol.
  doi: 10.1016/0192-0561(89)90187-2
  contributor:
    fullname: del Gobbo
– volume: 10
  start-page: 569
  year: 2017
  ident: B37
  article-title: Adiponectin and its receptors are differentially expressed in human tissues and cell lines of distinct origin.
  publication-title: Obes. Facts
  doi: 10.1159/000481732
  contributor:
    fullname: Jasinski-Bergner
– volume: 8
  start-page: 120
  year: 2016
  ident: B54
  article-title: Adiponectin: a versatile player of innate immunity.
  publication-title: J. Mol. Cell. Biol.
  doi: 10.1093/jmcb/mjw012
  contributor:
    fullname: Luo
– volume: 31
  start-page: 3
  year: 2020
  ident: B28
  article-title: Natural killer cells as sensors of adipose tissue stress.
  publication-title: Trends Endocrinol. Metab.
  doi: 10.1016/j.tem.2019.08.011
  contributor:
    fullname: Ferno
– volume: 88
  start-page: 2838
  year: 2003
  ident: B30
  article-title: Diurnal and ultradian dynamics of serum adiponectin in healthy men: comparison with leptin, circulating soluble leptin receptor, and cortisol patterns.
  publication-title: J. Clin. Endocrinol. Metab.
  doi: 10.1210/jc.2002-021721
  contributor:
    fullname: Gavrila
– volume: 16
  start-page: 442
  year: 2019
  ident: B78
  article-title: Sensing of physiological regulators by innate lymphoid cells.
  publication-title: Cell. Mol. Immunol.
  doi: 10.1038/s41423-019-0217-1
  contributor:
    fullname: Seillet
– volume: 133
  start-page: 11
  year: 2003
  ident: B70
  article-title: Role of leptin as an immunomodulator of blood mononuclear cells: mechanisms of action.
  publication-title: Clin. Exp. Immunol.
  doi: 10.1046/j.1365-2249.2003.02190.x
  contributor:
    fullname: Sanchez-Margalet
– volume: 68
  start-page: 48
  ident: B77
  article-title: Natural killers or ILC1s? That is the question.
  publication-title: Curr. Opin. Immunol.
  doi: 10.1016/j.coi.2020.08.009
  contributor:
    fullname: Seillet
– volume: 298
  start-page: 297
  year: 2002
  ident: B87
  article-title: Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation.
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/s0006-291x(02)02462-2
  contributor:
    fullname: Tian
– volume: 116
  start-page: 337
  year: 2004
  ident: B29
  article-title: Obesity wars: molecular progress confronts an expanding epidemic.
  publication-title: Cell
  doi: 10.1016/S0092-8674(03)01081-X
  contributor:
    fullname: Flier
– volume: 48
  start-page: 286
  year: 2018
  ident: B81
  article-title: Glucocorticoids drive diurnal oscillations in T cell distribution and responses by inducing interleukin-7 receptor and CXCR4.
  publication-title: Immunity
  doi: 10.1016/j.immuni.2018.01.004
  contributor:
    fullname: Shimba
– volume: 23
  start-page: 770
  year: 2016
  ident: B83
  article-title: Adiponectin, leptin, and fatty acids in the maintenance of metabolic homeostasis through adipose tissue crosstalk.
  publication-title: Cell Metab.
  doi: 10.1016/j.cmet.2016.04.011
  contributor:
    fullname: Stern
– volume: 188
  start-page: 2583
  year: 2012
  ident: B52
  article-title: Chronic shift-lag alters the circadian clock of NK cells and promotes lung cancer growth in rats.
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.1102715
  contributor:
    fullname: Logan
– volume: 33
  start-page: 708
  year: 2008
  ident: B7
  article-title: Are circadian rhythms the code of hypothalamic-immune communication? Insights from natural killer cells.
  publication-title: Neurochem. Res.
  doi: 10.1007/s11064-007-9501-z
  contributor:
    fullname: Arjona
– volume: 11
  year: 2020
  ident: B88
  article-title: Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations.
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-020-17197-2
  contributor:
    fullname: Todd
– volume: 302
  start-page: E108
  year: 2012
  ident: B98
  article-title: Short-term and long-term leptin exposure differentially affect human natural killer cell immune functions.
  publication-title: Am. J. Physiol. Endocrinol. Metab.
  doi: 10.1152/ajpendo.00057.2011
  contributor:
    fullname: Wrann
– volume: 8
  start-page: 476
  year: 2005
  ident: B8
  article-title: Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons.
  publication-title: Nat. Neurosci.
  doi: 10.1038/nn1419
  contributor:
    fullname: Aton
– volume: 217
  year: 2020
  ident: B96
  article-title: Beta2-adrenergic signals downregulate the innate immune response and reduce host resistance to viral infection.
  publication-title: J. Exp. Med.
  doi: 10.1084/jem.20190554
  contributor:
    fullname: Wieduwild
– volume: 201
  start-page: 1267
  year: 2018
  ident: B80
  article-title: Glucocorticoids inhibit group 3 innate lymphocyte IL-22 production.
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.1800484
  contributor:
    fullname: Seshadri
– volume: 5
  start-page: 195
  year: 1992
  ident: B9
  article-title: VIP restores natural killer cell activity depressed by hepatitis B surface antigen.
  publication-title: Viral Immunol.
  doi: 10.1089/vim.1992.5.195
  contributor:
    fullname: Azzari
– volume: 104
  start-page: 101
  year: 2000
  ident: B18
  article-title: Exogenous melatonin: quantitative enhancement in vivo of cells mediating non-specific immunity.
  publication-title: J. Neuroimmunol.
  doi: 10.1016/s0165-5728(99)00271-4
  contributor:
    fullname: Currier
– volume: 36
  start-page: 1167
  year: 2019
  ident: B39
  article-title: Melatonin research in mice: a review.
  publication-title: Chronobiol. Int.
  doi: 10.1080/07420528.2019.1624373
  contributor:
    fullname: Kennaway
– volume: 228
  start-page: 1202
  year: 2013
  ident: B44
  article-title: Leptin modulates dose-dependently the metabolic and cytolytic activities of NK-92 cells.
  publication-title: J. Cell. Physiol.
  doi: 10.1002/jcp.24273
  contributor:
    fullname: Lamas
– volume: 394
  start-page: 897
  year: 1998
  ident: B53
  article-title: Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression.
  publication-title: Nature
  doi: 10.1038/29795
  contributor:
    fullname: Lord
– volume: 111
  start-page: 16219
  year: 2014
  ident: B102
  article-title: A circadian gene expression atlas in mammals: implications for biology and medicine.
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.1408886111
  contributor:
    fullname: Zhang
– volume: 217
  year: 2020
  ident: B24
  article-title: Cell-intrinsic adrenergic signaling controls the adaptive NK cell response to viral infection.
  publication-title: J. Exp. Med.
  doi: 10.1084/jem.20190549
  contributor:
    fullname: Diaz-Salazar
– volume: 6
  year: 2016
  ident: B64
  article-title: Effects of systemically administered hydrocortisone on the human immunome.
  publication-title: Sci. Rep.
  contributor:
    fullname: Olnes
– volume: 20
  start-page: 720
  year: 2020
  ident: B94
  article-title: Keeping time in group 3 innate lymphoid cells.
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/s41577-020-0397-z
  contributor:
    fullname: Wang
– volume: 2020
  year: 2020
  ident: B95
  article-title: Leptin promoted IL-17 production from ILC2s in allergic rhinitis.
  publication-title: Mediators Inflamm.
  doi: 10.1155/2020/9248479
  contributor:
    fullname: Wen
– volume: 20
  start-page: 469
  year: 2006
  ident: B6
  article-title: Evidence supporting a circadian control of natural killer cell function.
  publication-title: Brain Behav. Immun.
  doi: 10.1016/j.bbi.2005.10.002
  contributor:
    fullname: Arjona
– volume: 17
  start-page: 8530
  year: 2018
  ident: B84
  article-title: Norepinephrine inhibits the cytotoxicity of NK92MI cells via the beta2adrenoceptor/cAMP/PKA/pCREB signaling pathway.
  publication-title: Mol. Med. Rep.
  contributor:
    fullname: Sun
– volume: 300
  start-page: 247
  year: 2003
  ident: B103
  article-title: Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines.
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/s0006-291x(02)02838-3
  contributor:
    fullname: Zhao
– volume: 4
  start-page: 1273
  year: 2014
  ident: B82
  article-title: HPA axis-rhythms.
  publication-title: Compr Physiol
  doi: 10.1002/cphy.c140003
  contributor:
    fullname: Spiga
– volume: 418
  start-page: 935
  year: 2002
  ident: B69
  article-title: Coordination of circadian timing in mammals.
  publication-title: Nature
  doi: 10.1038/nature00965
  contributor:
    fullname: Reppert
– volume: 62
  start-page: 593
  year: 2003
  ident: B19
  article-title: Circadian rhythms in RA.
  publication-title: Ann. Rheum. Dis.
  doi: 10.1136/ard.62.7.593
  contributor:
    fullname: Cutolo
– volume: 176
  start-page: 5958
  year: 2006
  ident: B43
  article-title: Adiponectin is a negative regulator of NK cell cytotoxicity.
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.176.10.5958
  contributor:
    fullname: Kim
– volume: 25
  start-page: 101
  year: 2011
  ident: B51
  article-title: Role of sympathetic nervous system in the entrainment of circadian natural-killer cell function.
  publication-title: Brain Behav. Immun.
  doi: 10.1016/j.bbi.2010.08.007
  contributor:
    fullname: Logan
– volume: 15
  start-page: 995
  year: 2001
  ident: B58
  article-title: Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism.
  publication-title: Genes Dev.
  doi: 10.1101/gad.873501
  contributor:
    fullname: Mitsui
– volume: 36
  start-page: 3142
  year: 2012
  ident: B92
  article-title: Ultradian corticosterone secretion is maintained in the absence of circadian cues.
  publication-title: Eur. J. Neurosci.
  doi: 10.1111/j.1460-9568.2012.08213.x
  contributor:
    fullname: Waite
– volume: 41
  start-page: 776
  year: 2014
  ident: B72
  article-title: The chemokine receptor CXCR6 controls the functional topography of interleukin-22 producing intestinal innate lymphoid cells.
  publication-title: Immunity
  doi: 10.1016/j.immuni.2014.10.007
  contributor:
    fullname: Satoh-Takayama
– volume: 579
  start-page: 575
  year: 2020
  ident: B86
  article-title: Feeding-dependent VIP neuron-ILC3 circuit regulates the intestinal barrier.
  publication-title: Nature
  doi: 10.1038/s41586-020-2039-9
  contributor:
    fullname: Talbot
– start-page: 145
  year: 1988
  ident: B2
  article-title: Effect of exogenous melatonin on human natural killer (NK) cell activity. An approach to the immunomodulatory role of the pineal gland
  publication-title: The Pineal Gland and Cancer
  contributor:
    fullname: Angeli
– volume: 184
  start-page: 503
  year: 2010
  ident: B25
  article-title: Selective mobilization of cytotoxic leukocytes by epinephrine.
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.0902189
  contributor:
    fullname: Dimitrov
– volume: 336
  start-page: 1391
  year: 1990
  ident: B76
  article-title: Regular inhaled beta-agonist treatment in bronchial asthma.
  publication-title: Lancet
  doi: 10.1016/0140-6736(90)93098-a
  contributor:
    fullname: Sears
– volume: 2020
  year: 2020
  ident: B101
  article-title: Leptin regulated ILC2 Cell through the PI3K/AKT pathway in allergic rhinitis.
  publication-title: Mediators Inflamm.
  doi: 10.1155/2020/4176082
  contributor:
    fullname: Zeng
– volume: 174
  start-page: 7618
  year: 2005
  ident: B5
  article-title: Circadian oscillations of clock genes, cytolytic factors, and cytokines in rat NK cells.
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.174.12.7618
  contributor:
    fullname: Arjona
– volume: 30
  start-page: 401
  year: 2007
  ident: B26
  article-title: Number and function of circulating human antigen presenting cells regulated by sleep.
  publication-title: Sleep
  doi: 10.1093/sleep/30.4.401
  contributor:
    fullname: Dimitrov
– volume: 9
  year: 2020
  ident: B89
  article-title: An adipokine feedback regulating diurnal food intake rhythms in mice.
  publication-title: Elife
  doi: 10.7554/eLife.55388
  contributor:
    fullname: Tsang
– volume: 172
  start-page: 2811
  year: 2004
  ident: B4
  article-title: Circadian rhythms of granzyme B, perforin, IFN-gamma, and NK cell cytolytic activity in the spleen: effects of chronic ethanol.
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.172.5.2811
  contributor:
    fullname: Arjona
– volume: 12
  year: 2017
  ident: B41
  article-title: Differential adipokine receptor expression on circulating leukocyte subsets in lean and obese children.
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0187068
  contributor:
    fullname: Keustermans
– volume: 12
  start-page: 320
  year: 2011
  ident: B73
  article-title: RORgammat+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota.
  publication-title: Nat. Immunol.
  doi: 10.1038/ni.2002
  contributor:
    fullname: Sawa
– volume: 69
  start-page: 543
  year: 2001
  ident: B56
  article-title: Presence of melatonin in the human hepatobiliary-gastrointestinal tract.
  publication-title: Life Sci.
  doi: 10.1016/s0024-3205(01)01143-2
  contributor:
    fullname: Messner
– volume: 11
  year: 2019
  ident: B65
  article-title: Dysregulation of natural killer cells in obesity.
  publication-title: Cancers (Basel)
  doi: 10.3390/cancers11040573
  contributor:
    fullname: O’Shea
– volume: 21
  start-page: 168
  ident: B79
  article-title: The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity.
  publication-title: Nat. Immunol.
  doi: 10.1038/s41590-019-0567-y
  contributor:
    fullname: Seillet
– volume: 83
  start-page: 1706
  year: 1998
  ident: B45
  article-title: Circadian rhythm of plasma leptin levels in upper and lower body obese women: influence of body fat distribution and weight loss.
  publication-title: J. Clin. Endocrinol. Metab.
  doi: 10.1210/jcem.83.5.4717
  contributor:
    fullname: Langendonk
– volume: 7
  start-page: 153
  year: 1989
  ident: B47
  article-title: Melatonin-induced suppression of human lymphocyte natural killer activity in vitro.
  publication-title: J. Pineal Res.
  doi: 10.1111/j.1600-079x.1989.tb00663.x
  contributor:
    fullname: Lewinski
– volume: 264
  start-page: 582
  year: 1994
  ident: B57
  article-title: Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor.
  publication-title: Science
  doi: 10.1126/science.8160017
  contributor:
    fullname: Milano
– volume: 40
  start-page: 323
  year: 1987
  ident: B20
  article-title: Daily variations in plasma noradrenaline, adrenaline and corticosterone concentrations in rats.
  publication-title: Physiol. Behav.
  doi: 10.1016/0031-9384(87)90054-0
  contributor:
    fullname: De Boer
– volume: 57
  start-page: 134
  year: 2015
  ident: B21
  article-title: Sleep-deprivation reduces NK cell number and function mediated by beta-adrenergic signalling.
  publication-title: Psychoneuroendocrinology
  doi: 10.1016/j.psyneuen.2015.04.006
  contributor:
    fullname: De Lorenzo
– volume: 60
  start-page: 1210
  year: 1985
  ident: B49
  article-title: Circadian rhythms of epinephrine and norepinephrine in man.
  publication-title: J. Clin. Endocrinol. Metab.
  doi: 10.1210/jcem-60-6-1210
  contributor:
    fullname: Linsell
– volume: 6
  year: 2011
  ident: B3
  article-title: Rhythmic leptin is required for weight gain from circadian desynchronized feeding in the mouse.
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0025079
  contributor:
    fullname: Arble
– volume: 291
  start-page: 22043
  year: 2016
  ident: B104
  article-title: Leptin enhances TH2 and ILC2 responses in allergic airway disease.
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.m116.743187
  contributor:
    fullname: Zheng
– volume: 287
  start-page: R1071
  year: 2004
  ident: B15
  article-title: Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation.
  publication-title: Am. J. Physiol. Regul. Integr. Comp. Physiol.
  doi: 10.1152/ajpregu.00294.2004
  contributor:
    fullname: Bodosi
– volume: 12
  start-page: 1045
  year: 2011
  ident: B60
  article-title: Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus.
  publication-title: Nat. Immunol.
  doi: 10.1038/ni.2131
  contributor:
    fullname: Monticelli
– volume: 103
  start-page: 2998
  year: 2018
  ident: B90
  article-title: Circadian rhythm of glucocorticoid administration entrains clock genes in immune cells: a DREAM Trial Ancillary study.
  publication-title: J. Clin. Endocrinol. Metab.
  doi: 10.1210/jc.2018-00346
  contributor:
    fullname: Venneri
– volume: 6
  year: 2017
  ident: B31
  article-title: Circadian rhythms and hormonal homeostasis: pathophysiological implications.
  publication-title: Biology (Basel)
  contributor:
    fullname: Gnocchi
– volume: 289
  start-page: 2344
  year: 2000
  ident: B11
  article-title: Resetting of circadian time in peripheral tissues by glucocorticoid signaling.
  publication-title: Science
  doi: 10.1126/science.289.5488.2344
  contributor:
    fullname: Balsalobre
– volume: 13
  year: 2015
  ident: B48
  article-title: Suppression of dendritic cell-derived IL-12 by endogenous glucocorticoids is protective in LPS-induced sepsis.
  publication-title: PLoS Biol.
  doi: 10.1371/journal.pbio.1002269
  contributor:
    fullname: Li
– volume: 218
  year: 2021
  ident: B93
  article-title: Adiponectin restrains ILC2 activation by AMPK-mediated feedback inhibition of IL-33 signaling.
  publication-title: J. Exp. Med.
  doi: 10.1084/jem.20191054
  contributor:
    fullname: Wang
– volume: 22
  start-page: 448
  year: 2015
  ident: B40
  article-title: Circadian dysfunction induces leptin resistance in mice.
  publication-title: Cell Metab.
  doi: 10.1016/j.cmet.2015.06.005
  contributor:
    fullname: Kettner
– volume: 514
  start-page: 638
  year: 2014
  ident: B67
  article-title: Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness.
  publication-title: Nature
  doi: 10.1038/nature13823
  contributor:
    fullname: Pickard
– volume: 19
  start-page: 954
  year: 2018
  ident: B68
  article-title: Endogenous glucocorticoids control host resistance to viral infection through the tissue-specific regulation of PD-1 expression on NK cells.
  publication-title: Nat. Immunol.
  doi: 10.1038/s41590-018-0185-0
  contributor:
    fullname: Quatrini
– volume: 18
  start-page: 461
  year: 2001
  ident: B75
  article-title: Cardiovascular regulation in TGR(mREN2)27 rats: 24h variation in plasma catecholamines, angiotensin peptides, and telemetric heart rate variability.
  publication-title: Chronobiol. Int.
  doi: 10.1081/cbi-100103969
  contributor:
    fullname: Schiffer
– volume: 6
  start-page: 1170
  year: 1996
  ident: B13
  article-title: A role for leptin and its cognate receptor in hematopoiesis.
  publication-title: Curr. Biol.
  doi: 10.1016/s0960-9822(02)70684-2
  contributor:
    fullname: Bennett
– volume: 26
  start-page: 241
  year: 2007
  ident: B22
  article-title: A key role of leptin in the control of regulatory T cell proliferation.
  publication-title: Immunity
  doi: 10.1016/j.immuni.2007.01.011
  contributor:
    fullname: De Rosa
– volume: 23
  start-page: 2233
  year: 2015
  ident: B36
  article-title: Decreased NK cell functions in obesity can be reactivated by fat mass reduction.
  publication-title: Obesity (Silver Spring)
  doi: 10.1002/oby.21229
  contributor:
    fullname: Jahn
– volume: 106
  start-page: 4453
  year: 2009
  ident: B74
  article-title: Adverse metabolic and cardiovascular consequences of circadian misalignment.
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.0808180106
  contributor:
    fullname: Scheer
– volume: 12
  start-page: 631
  year: 2011
  ident: B17
  article-title: Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.
  publication-title: Nat. Immunol.
  doi: 10.1038/ni.2045
  contributor:
    fullname: Chang
– volume: 142
  start-page: 2677
  year: 2001
  ident: B38
  article-title: The suprachiasmatic nucleus generates the diurnal changes in plasma leptin levels.
  publication-title: Endocrinology
  doi: 10.1210/endo.142.6.8197
  contributor:
    fullname: Kalsbeek
– volume: 2013
  year: 2013
  ident: B100
  article-title: Understanding dendritic cells and their role in cutaneous carcinoma and cancer immunotherapy.
  publication-title: Clin. Dev. Immunol.
  doi: 10.1155/2013/624123
  contributor:
    fullname: Yanofsky
– volume: 151
  start-page: 115
  year: 2010
  ident: B32
  article-title: Circadian expression of adiponectin and its receptors in human adipose tissue.
  publication-title: Endocrinology
  doi: 10.1210/en.2009-0647
  contributor:
    fullname: Gomez-Abellan
– volume: 43
  start-page: 527
  year: 2004
  ident: B71
  article-title: A functional genomics strategy reveals Rora as a component of the mammalian circadian clock.
  publication-title: Neuron
  doi: 10.1016/j.neuron.2004.07.018
  contributor:
    fullname: Sato
– volume: 85
  start-page: 21
  year: 1988
  ident: B66
  article-title: Circadian variations in chronic asthma and chronic obstructive pulmonary disease.
  publication-title: Am. J. Med.
  doi: 10.1016/0002-9343(88)90237-9
  contributor:
    fullname: Petty
– volume: 174
  start-page: 1054
  year: 2018
  ident: B91
  article-title: Innate lymphoid cells: 10 years on.
  publication-title: Cell
  doi: 10.1016/j.cell.2018.07.017
  contributor:
    fullname: Vivier
– volume: 109
  start-page: 4313
  year: 2007
  ident: B14
  article-title: Macrophage glucocorticoid receptors regulate Toll-like receptor 4-mediated inflammatory responses by selective inhibition of p38 MAP kinase.
  publication-title: Blood
  doi: 10.1182/blood-2006-10-048215
  contributor:
    fullname: Bhattacharyya
– volume: 119
  start-page: 2760
  year: 2006
  ident: B61
  article-title: Severe pulmonary metastasis in obese and diabetic mice.
  publication-title: Int. J. Cancer
  doi: 10.1002/ijc.22248
  contributor:
    fullname: Mori
– start-page: 91
  year: 1996
  ident: B16
  article-title: Cytokine modulation by glucocorticoids: mechanisms and actions in cellular studies.
  publication-title: Aliment. Pharmacol. Ther.
  contributor:
    fullname: Brattsand
– volume: 359
  start-page: 1056
  year: 2018
  ident: B62
  article-title: beta2-adrenergic receptor-mediated negative regulation of group 2 innate lymphoid cell responses.
  publication-title: Science
  doi: 10.1126/science.aan4829
  contributor:
    fullname: Moriyama
– volume: 43
  start-page: 1024
  year: 2013
  ident: B97
  article-title: Adiponectin modulates NK-cell function.
  publication-title: Eur. J. Immunol.
  doi: 10.1002/eji.201242382
  contributor:
    fullname: Wilk
– volume: 74
  start-page: 4750
  year: 2006
  ident: B50
  article-title: The circadian clock Period 2 gene regulates gamma interferon production of NK cells in host response to lipopolysaccharide-induced endotoxic shock.
  publication-title: Infect. Immun.
  doi: 10.1128/iai.00287-06
  contributor:
    fullname: Liu
– volume: 210
  start-page: 535
  year: 2013
  ident: B59
  article-title: Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages.
  publication-title: J. Exp. Med.
  doi: 10.1084/jem.20121964
  contributor:
    fullname: Molofsky
– volume: 399
  start-page: 284
  year: 2015
  ident: B12
  article-title: The circadian clock machinery controls adiponectin expression.
  publication-title: Mol. Cell. Endocrinol.
  doi: 10.1016/j.mce.2014.10.018
  contributor:
    fullname: Barnea
– volume: 104
  start-page: 1051
  year: 1999
  ident: B35
  article-title: Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice.
  publication-title: J. Clin. Invest.
  doi: 10.1172/jci6762
  contributor:
    fullname: Howard
– volume: 502
  start-page: 245
  year: 2013
  ident: B63
  article-title: Type 2 innate lymphoid cells control eosinophil homeostasis.
  publication-title: Nature
  doi: 10.1038/nature12526
  contributor:
    fullname: Nussbaum
SSID ssj0062842
Score 2.3589823
SecondaryResourceType review_article
Snippet The Earth's rotation around its axis, is one of the parameters that never changed since life emerged. Therefore, most of the organisms from the cyanobacteria...
The Earth’s rotation around its axis, is one of the parameters that never changed since life emerged. Therefore, most of the organisms from the cyanobacteria...
SourceID doaj
pubmedcentral
proquest
crossref
pubmed
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
StartPage 657081
SubjectTerms Animal models
Asthma
Biological clocks
Catecholamines
Circadian rhythm
Circadian rhythms
Cytokines
Cytotoxicity
Diurnal variations
Food
Homeostasis
Hormones
Immune response
Inflammation
Lymphoid cells
Nervous system
neuroimmune interactions
neuropeptide
Neuropeptides
Neuroscience
Oscillations
Pathogens
Transcription factors
Viral infections
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Na9wwEBUlp15Km_TDTRpUKD0U3NiSLEvHJCSkpe0hNJCbsaQRa0i0pdkc9t93RtpdsqXQS66WsOU3kuaNNHpi7EOUnYaInVf3QtVKKKjH2MdaBKMjjK3xWdTn-w99caW-XnfXD676opywIg9cgDsKOjY6tA5E7JQE4YKJoVOeqEzsPOTZtxHrYKrMwRonXVH2MDEEs0cxTYm0uUX7mVI9TLvlhbJY_78Y5t-Jkg88z_lz9mxFGflxaeoL9gTSLts7Thgu3y75R56TOPPq-B77ksU2Jjr0ATyv9pWDC3d8TIFfzpaL2e3k-WW5gR4L-DxiPXwX8G9LtOx8CvwUbm7uXrKr87Ofpxf16raE2isrFzX4YL2TxgSHIV2QIkjtXe96DDKCtAGEQIo6NsoHNypwyDScNTQebRDkwF6xnTRP8IbxAA3C3nc-aKOCAasienlofKTVD-kq9mmN3vCriGIMGEwQ1EOGeiCohwJ1xU4I301F0rPOD9DKw8rKw_-sXLGDtXWG1SDDj5AyjkaS0Vfs_aYYhwfteYwJ5vdUB7uCJBZVsdfFmJuWSCRnCF1TsX7LzFtN3S5J0yxLcJu21bZr3j7Gv-2zpwQXbVEJe8B2Fr_v4R0ynYU7zJ36D4oz_3Y
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: ProQuest Central
  dbid: BENPR
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1La9wwEB7azaWXkjZ9uEmLCqWHghtbkmX5VJKQkJY2lKWB3Iz16hoSO8luDvvvMyN7l24JuVrCEt9Imm8eGgF8CqJQPuDiVSWXqeTSp00oQ8qdVsE3ubaxqM-vM3V6Ln9cFBejw20-plWuzsR4ULveko98n25Yonbmsvx2fZPSq1EUXR2f0HgKWzwXWk9g6_D47Pd0dRYrPHxjvFPR3SAk50NcE82yaj90bUf1unn-ldI_dL6hmWIB_4dY5__Jk_9oo5NteD7SSHYwyP0FPPHdS9g56NCEvlqyzywmdkaP-Q58jwU4WroI4ln0AA6XGeas6RybzpaL2VVr2XR4lR4bWB-wH_7Ls59LlHbfOnbkLy_nr-D85PjP0Wk6vqCQWlmJReqtq6xBYJxBM88J7oSypjQlGh5OVM5zjrS1yaR1ppHeIPswlaY9WjlOSu01TLq-82-BOZ85FcrCOqWl076SATW_z2wgj4gwCXxZoVdfD4UyajQwCOo6Ql0T1PUAdQKHhO-6I9W4jh_627_1uGVqHC5TLjeeh0IKz43TwRXSEokNhfUJ7K2kU48bDwdZL5MEPq6bcctQHKTpfH9HfXBZCGJWCbwZhLmeiUDChtBlCZQbYt6Y6mZL185iWW6d56oqsnePT2sXnhEQFJDi1R5MFrd3_j3ymoX5MC7ee34f-Rg
  priority: 102
  providerName: ProQuest
– databaseName: Scholars Portal Open Access Journals
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Lb9QwELaqcuGCgPIIFGQkxAEpJbEdxzkgVCqqgiiHipV6s2J7zEbaJrC7ldh_z4yzu2LRHrjGlm19Hme-8TzM2OsoKw0RhVfXQuVKKMjbWMdcBKMjtKXxqajP5Td9MVFfrqvrA7Z53moN4GKvaUfvSU3ms5Pfv1Yf8MC_J4sT9e272Hc9Vd4W5QkFclAi9h2BipEivC7V1qmg8U-cnJ-aEoWQqY9Ozv1D7KipVM1_HwX9N5LyL9V0fp_dW3NKfjoKwQN2AP1DdnTaoz19s-JveIryTNfnR-xzqsbRUVYI8HQdOGY2LHjbB341XS2nN53nV-MT9djAh4j9cCzgX1e49UMX-BnMZotHbHL-6fvZRb5-TiH3qpHLHHxovJPGBIc2X5AiSO1d7Wq0QoJsAgiBHLYtlA-uVeCQirjG0IFtgiAN95gd9kMPTxkPUAQd68oHbVQw0KiINAAKH-l6RLqMvd2gZ3-OVTMsWhsEtU1QW4LajlBn7CPhu-1IBa_Th2H-w67Pj8XpCh1KByJWSoJwwcRQKU-MNlYeMna82R27ESJLWbnI6ISqM_Zq24znh5wibQ_DLfVBsZBEszL2ZNzM7UoksjeErshYvbPNO0vdbem7aarRbcpSN1Xx7D_mfc7uEhrkohLNMTtczm_hBTKdpXuZ5PcP15r9nQ
  priority: 102
  providerName: Scholars Portal
Title Neuroimmune Interactions and Rhythmic Regulation of Innate Lymphoid Cells
URI https://www.ncbi.nlm.nih.gov/pubmed/33994930
https://www.proquest.com/docview/2519560247
https://search.proquest.com/docview/2528431028
https://pubmed.ncbi.nlm.nih.gov/PMC8116950
https://doaj.org/article/d6f06d1be2f543e2bd8fd54c0115f5ce
Volume 15
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9swDCba7rLLsK17eOsCDRh2GODElmVZPrZBu25YiiJYgdwM69UYSOSiTQ_596NkO2iGnXbRwZItmaTEjxRFAXyxWc6NReHlBWUxo8zEtS1sTLXg1tSpUCGpz-yKX96wn4t8cQD5cBYmBO0r2Yzdaj12zTLEVt6t1WSIE5tcz6YiTXmZJ5NDOET1O5jo3fLLcb0NW5zcHwdCPN5tZaIlVk6sa5xP0U3TsY_4EP6amAw1NCt9EPQTvRTS9_8Lc_4dOvlEF128hBc9iCSn3WBfwYFxr-H41KEBvd6SrySEdQZ_-TH8COk3Gn8MxJDg_-uOMjyQ2mkyX243y3WjyLy7kx4rSGuxHX7LkF9b5HXbaDI1q9XDG7i5OP89vYz7-xNihX-0iY3SpZKZEFqikaczqjOuZCELNDt0VmpDKYLWOmFKy5oZidhDlsLP0FJTr9LewpFrnXkPRJtEc1vkSnPBtDAls6j3TaKs94dkMoJvA_Wquy5NRoXmhad6FaheeapXHdUjOPP03TX0Ga7Dg_b-tur5XGF3CdepNNTmLDNUamF1zpSHsDZXJoKTgTtVP-2wE58rhyPsKCL4vKvGCeN3QWpn2kffBiUk87gqgncdM3cjGYQhgmKPzXtD3a9BGQ1JuXuZ_PDfb36E555GfqeKlidwtLl_NJ8Q8GzkCJ6dnV9dz0fBYYDl90WK5YyJURD9P1MlBRc
link.rule.ids 230,314,727,780,784,864,885,2102,21388,24318,27924,27925,33744,33745,43805,53791,53793,74302
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwEB7B9gAXBJRHoICREAek0MR2nOSE2qrVFrYrtGql3qL41Y3UJqW7Pey_Z8bJrliEuMZWbM14Zr55eAzwyYtMOY-HV-VcxpJLF9c-9zG3hfKuTgsTmvqcTdX4Qn6_zC6HgNtiKKtc68SgqG1nKEa-Tzcs0TpzmX-7_RXTq1GUXR2e0HgIO9Q5PRvBzuHx9OdsrYsVKt-Q71R0NwjBeZ_XRLes3Pdt01K_bp5-pfKPIt2yTKGB_79Q59_Fk39Yo5On8GSAkeyg5_szeODa57B70KILfbNin1ko7AwR8104DQ04GroI4liIAPaXGRasbi2bzVfL-U1j2Kx_lR4HWOdxHv7LsckKud01lh256-vFC7g4OT4_GsfDCwqxkaVYxs7Y0mhRFFajm2cFt0IZnescHQ8rSus4R9haJ9JYXUunEX3osiAZLS0no_YSRm3XutfArEus8nlmrCqkLVwpPVp-lxhPERGhI_iypl512zfKqNDBIFJXgdQVkbrqSR3BIdF3M5F6XIcP3d1VNYhMhcslyqbacZ9J4bi2hbeZNARifWZcBHtr7lSD4OEim2MSwcfNMIoM5UHq1nX3NAePhSBkFcGrnpmbnQgEbEi6JIJ8i81bW90eaZt5aMtdpKkqs-TN_7f1AR6Nz88m1eR0-uMtPCaiUHKKl3swWt7du3eIcZb6_XCQfwNFefwA
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3db9QwDLfgJiFeEDBghQFBQjwglWvTNE2f0DZ22mCcphOT9lY1X1ylrR2728P999hp78QhxGsTNZHt2D_Hjg3w3me5dB6FVxZcxIILF9e-8DG3SnpXp8qEoj7fp_LkQny9zC-H_KfFkFa51olBUdvO0B35mF5YonXmohj7IS3i_Mvk882vmDpIUaR1aKdxH3bQKiZ8BDuHx9Pz2VovS1TEIfYp6Z0QAvU-xokuWjn2bdNS7W6efqJUEJVuWalQzP9fCPTvRMo_LNPkMTwaICU76GXgCdxz7VPYPWjRnb5esQ8sJHmG2_NdOA3FOBp6FOJYuA3sHzYsWN1aNpuvlvPrxrBZ36EeB1jncR7-y7GzFXK-ayw7cldXi2dwMTn-cXQSD90UYiPKbBk7Y0ujM6WsRpfPZtxm0uhCF-iE2Ky0jnOEsHUijNW1cBqRiC4VndfScjJwz2HUdq3bA2ZdYqUvcmOlEla5UnhEAS4xnm5HMh3BxzX1qpu-aEaFzgaRugqkrojUVU_qCA6JvpuJVO86fOhuf1bD8alwuUTaVDvuc5E5rq3yNheGAK3PjYtgf82dajiEuMhGZCJ4txnG40Mxkbp13R3NQbHICGVF8KJn5mYnGYI3JF0SQbHF5q2tbo-0zTyU6FZpKss8efn_bb2FByjD1dnp9NsreEg0oTgVL_dhtLy9c68R7iz1m0GOfwPqxgA8
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Neuroimmune+Interactions+and+Rhythmic+Regulation+of+Innate+Lymphoid+Cells&rft.jtitle=Frontiers+in+neuroscience&rft.au=Jacquelot%2C+Nicolas&rft.au=Belz%2C+Gabrielle+T&rft.au=Seillet%2C+Cyril&rft.date=2021-04-29&rft.issn=1662-4548&rft.volume=15&rft.spage=657081&rft.epage=657081&rft_id=info:doi/10.3389%2Ffnins.2021.657081&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1662-4548&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1662-4548&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1662-4548&client=summon