Enhancing the Immune Response of a Nicotine Vaccine with Synthetic Small “Non-Natural” Peptides - Le, Hoang-Thanh; Fraleigh, Nya L.; Lewicky, Jordan D.; Boudreau, Justin; Dolinar, Paul; Bhardwaj, Nitin; Diaz-Mitoma, Francisco; Montaut, Sabine; Fallahi, Sarah; Martel, Alexandrine L. (Molecules (Basel, Switzerland), 2020)
Keywords: Adjuvants, Immunologic - pharmacology; Animals; Antigen presentation; bacterial derived adjuvant; Chromatography, High Pressure Liquid; Cytokines; dendritic cells; Drug Delivery Systems; Haptens - drug effects; Haptens - immunology; Hepatitis; Humans; il-1β; Immune response; immune responses; Immunity - drug effects; Immunity - immunology; Immunomodulators; Influenza; Interleukin-1beta - genetics; macrophages; Mice; Nicotine; Nicotine - immunology; Nicotine - metabolism; non-natural peptides; peptide solid phase synthesis; Peptides; Peptides - immunology; Peptides - pharmacology; phagocytic cells; Proteins; Substance-Related Disorders - genetics; Substance-Related Disorders - immunology; Substance-Related Disorders - pathology; Substance-Related Disorders - prevention & control; Tobacco Use Disorder - genetics; Tobacco Use Disorder - immunology; Tobacco Use Disorder - prevention & control; vaccine delivery; Vaccines; Vaccines, Conjugate - immunology; Vaccines, Conjugate - pharmacology; Vaccines, Subunit - immunology; Vaccines, Subunit - pharmacology; vaccine delivery; macrophages; peptide solid phase synthesis; dendritic cells; bacterial derived adjuvant; non-natural peptides; IL-1β; immune responses; phagocytic cells