Mitochondrial mutations in maternally inherited hearing loss

• Published in: BMC medical genetics Vol. 18; no. 1; p. 32
• Main Authors: Mutai, Hideki, Watabe, Takahisa, Kosaki, Kenjiro, Ogawa, Kaoru, Matsunaga, Tatsuo
• Format: Journal Article
• Language: English
• Published: England BioMed Central 20.03.2017
• Subjects: Adult; Child; Deoxyribonucleic acid; DNA; DNA, Mitochondrial - genetics; Environmental factors; Female; Genes; Genetic testing; Genomes; Hearing loss; Hearing Loss, Sensorineural - genetics; Hearing protection; Humans; Male; Maternal Inheritance; Mitochondria - genetics; Mitochondrial DNA; Mutation; Otolaryngology; Sequence Analysis, DNA - methods; Young Adult; Mitochondrial deafness; Maternal inheritance; MTTS1

Although the mitochondrial DNA (mtDNA) mutations m.1555A > G and m.3243A > G are the primary causes of maternally inherited sensorineural hearing loss (SNHL), several other mtDNA mutations are also reported to be associated with SNHL. Screening of m.1555A > G and m.3243A > G mutations wa...