METTL3 enhances NSD2 mRNA stability to reduce renal impairment and interstitial fibrosis in mice with diabetic nephropathy - Tang, Weiming; Zhao, Yilin; Zhang, Hui; Peng, Ying; Rui, Zhilian (BMC nephrology, 2022)
Keywords: Analysis; Animal models; Animals; Blood pressure; Care and treatment; Creatinine; Cystatin C; Diabetes; Diabetes Mellitus; Diabetic nephropathies; Diabetic Nephropathies - genetics; Diabetic Nephropathies - metabolism; Diabetic nephropathy; Diagnosis; Disease; Feeds; Fibrosis; Gene expression; Glucagon; Glucose; Histone methyltransferase; Histone-Lysine N-Methyltransferase; Humans; Hyperglycemia; Hypertension; Insulin; Insulin secretion; Interstitial fibrosis; Kidneys; Laboratory animals; Males; Mesangial cells; Messenger RNA; Methyltransferases; Methyltransferases - genetics; Methyltransferases - metabolism; METTL3; Mice; mRNA stability; N6-methyladenosine; Nephrology; Nephropathy; NSD2; Patients; Proteins; Pulmonary fibrosis; Repressor Proteins; Risk factors; RNA modification; RNA Stability; RNA, Messenger - metabolism; Urine; YTHDF1; China; Beijing China; United States--US; Japan; Diabetic nephropathy; YTHDF1; Interstitial fibrosis; METTL3; NSD2