Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review

• Published in: Critical reviews in food science and nutrition Vol. 58; no. 6; pp. 924 - 941
• Main Authors: Gan, Ren-You, Li, Hua-Bin, Sui, Zhong-Quan, Corke, Harold
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 13.04.2018; Taylor & Francis Ltd
• Subjects: Absorption; Animals; anti-cancer effect; Anticancer properties; antineoplastic activity; Antineoplastic Agents - pharmacokinetics; Asia; Beverages; Bioactive compounds; Biological activity; Cancer; cancer stem cells; Catechin - analogs & derivatives; Catechin - pharmacokinetics; Cell Line, Tumor; chemoprevention; Drug Synergism; drug therapy; Epigallocatechin gallate; Green tea; gut microbiota; Humans; Intestinal microflora; intestinal microorganisms; Intestine; intestines; Metabolism; Microbiota; molecular targets; Nanoparticles; neoplasms; Neoplasms - prevention & control; Neoplastic Stem Cells - drug effects; Neoplastic Stem Cells - metabolism; polyphenols; Polyphenols - pharmacokinetics; Stem cells; Tea; Tea - chemistry; Asia; nanoparticles; cancer stem cells; anti-cancer effect; Metabolism; molecular targets; gut microbiota

Green tea is one of the most popular beverages in the world, especially in Asian countries. Consumption of green tea has been demonstrated to possess many health benefits, which mainly attributed to the main bioactive compound epigallocatechin gallate (EGCG), a flavone-3-ol polyphenol, in green tea....