Investigation of the Anti-Leishmania (Leishmania) infantum Activity of Some Natural Sesquiterpene Lactones - Wulsten, Imke; Costa-Silva, Thais; Mesquita, Juliana; Lima, Marta; Galuppo, Mariana; Taniwaki, Noemi; Borborema, Samanta; Da Costa, Fernando; Schmidt, Thomas; Tempone, Andre (Molecules (Basel, Switzerland), 2017)
Keywords: Animals; Antiprotozoal Agents - pharmacology; Bridged-Ring Compounds - pharmacology; Cells, Cultured; Drug Evaluation, Preclinical; drugs; Furans - pharmacology; helenalin acetate; Inhibitory Concentration 50; Lactones - pharmacology; Leishmania (L.) infantum; Leishmania infantum - drug effects; Leishmania infantum - ultrastructure; Leishmaniasis, Visceral - drug therapy; Macrophages, Peritoneal - drug effects; mexicanin I; Mice, Inbred BALB C; nitric oxide; Nitric Oxide - metabolism; Permeability; pseudoguaianolides; Reactive oxygen species; sesquiterpene lactones; Sesquiterpenes - pharmacology; Sesquiterpenes, Germacrane - pharmacology; mexicanin I; nitric oxide; Leishmania (L.) infantum; drugs; sesquiterpene lactones; pseudoguaianolides; helenalin acetate