New Indole Glycosides from Aesculus chinensis var. chekiangensis and Their Neuroprotective Activities

• Published in: Molecules (Basel, Switzerland) Vol. 24; no. 22; p. 4063
• Main Authors: Zhang, Nan, Cao, Shijie, Huang, Weixing, Li, Pan, Kang, Ning, Ding, Liqin, Qiu, Feng
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 09.11.2019; MDPI
• Subjects: Acids; Aesculus - chemistry; aesculus chinensis bge. var. chekiangensis (hu et fang) fang; Cell Line, Tumor; Cytotoxicity; Glucose; Glycosides - pharmacology; HCT116 Cells; Hep G2 Cells; Humans; Indoles - pharmacology; Medicine, Chinese Traditional - methods; n-glucosylated indoles; neuroprotective activity; Neuroprotective Agents - pharmacology; Nitrogen; Plant Extracts - pharmacology; Traditional Chinese medicine; United States > US; N-glucosylated indoles; neuroprotective activity; Aesculus chinensis Bge. var. chekiangensis (Hu et Fang) Fang
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules24224063

The dried seeds of Aesculus chinensis Bge. var. chekiangensis (Hu et Fang) Fang, called “Suo Luo Zi”, have been used in traditional Chinese medicine. Nevertheless, most studies have been focused on components of less polarity fractions. In this research, twelve indoles, including six new indole glyc...