Special review series on 3D organotypic culture models: Introduction and historical perspective

• Published in: In vitro cellular & developmental biology. Animal Vol. 57; no. 2; pp. 95 - 103
• Main Authors: Hayden, Patrick J., Harbell, John W.
• Format: Journal Article
• Language: English
• Published: Germany Springer Science & Business Media LLC 01.02.2021; Society for In Vitro Biology; Springer US
• Subjects: Animals; Biology; Bioprinting; Cell culture; Cell Culture Techniques - history; Cell Culture Techniques - methods; Cell differentiation; Cell interactions; Cell proliferation; Cellular structure; Differentiation (biology); History, 20th Century; Humans; In vivo methods and tests; Interrogation; INVITED REVIEW; Models, Biological; Monolayers; Organoids; Substrates; Three dimensional models; Biological matrix; Functional differentiation; Organotypic culture; iPSC

Three dimensional (3D) organ-like (organotypic) culture models are a rapidly advancing area of in vitro biological science. In contrast to monolayer cell culture methods which were developed to achieve proliferation of animal cells in the beginning of in vitro biology, the advancements in 3D culture...