Single Extracellular Vesicle Analysis Using Flow Cytometry for Neurological Disorder Biomarkers

• Published in: Frontiers in integrative neuroscience Vol. 16; p. 879832
• Main Authors: Ali Moussa, Houda Yasmine, Manaph, Nimshitha, Ali, Gowher, Maacha, Selma, Shin, Kyung Chul, Ltaief, Samia M, Gupta, Vijay, Tong, Yongfeng, Ponraj, Janarthanan, Salloum-Asfar, Salam, Mansour, Said, Al-Shaban, Fouad A, Kim, Hyung-Goo, Stanton, Lawrence W, Grivel, Jean-Charles, Abdulla, Sara A, Al-Shammari, Abeer R, Park, Yongsoo
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 17.05.2022; Frontiers Media S.A
• Subjects: Amino acids; Antibiotics; biomarker; Biomarkers; Blood-brain barrier; Brain-derived neurotrophic factor; CD63 antigen; Cell adhesion molecules; Cell interactions; Disease; exosome; Exosomes; extracellular vesicle; Flow cytometry; Growth factors; Horizontal cells; Horizontal transfer; Inhibitory postsynaptic potentials; Membrane vesicles; Microscopy; Nanoparticles; NCAM; Neural cell adhesion molecule; Neurological diseases; neurological disorder; Neurological disorders; Neuroscience; Organoids; Penicillin; Plasma; Pluripotency; Proteins; Stem cells; biomarker; NCAM; exosome; extracellular vesicle; neurological disorder

Extracellular vesicles (EVs) are membrane vesicles released from cells to the extracellular space, involved in cell-to-cell communication by the horizontal transfer of biomolecules such as proteins and RNA. Because EVs can cross the blood-brain barrier (BBB), circulating through the bloodstream and...