Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori - Fan, Tianyun; Guo, Xixi; Zeng, Qingxuan; Wei, Wei; You, Xuefu; Pang, Jing; Wang, Yanxiang; Song, Danqing (Molecules (Basel, Switzerland), 2020)
Keywords: Animals; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Bacteria; Berberine Alkaloids - chemistry; Berberine Alkaloids - pharmacology; Binding sites; Drug dosages; FDA approval; Gram-negative bacteria; helicobacter pylori; Helicobacter pylori - drug effects; Male; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; palmatine; Structure-Activity Relationship; synthesis; Toxicity Tests, Acute; Ulcers; urease; Urease - metabolism; synthesis; structure–activity relationship; palmatine; Helicobacter pylori; urease