Effect of Dibutyltin Dilaurate on Triglyceride Metabolism through the Inhibition of the mTOR Pathway in Human HL7702 Liver Cells - Qiao, Xiaozhi; Li, Yunlan; Mai, Jiaqi; Ji, Xiaoqing; Li, Qingshan (Molecules (Basel, Switzerland), 2018)
Keywords: Cell Line; Cell Survival - drug effects; dibutyltin dilaurate (DBTD); Dose-Response Relationship, Drug; Gene Expression Regulation - drug effects; Hepatocytes - cytology; Hepatocytes - drug effects; Hepatocytes - metabolism; Humans; Kinases; Lipid Metabolism - drug effects; Metabolism; mTOR pathway; Organotin Compounds - pharmacology; Phosphorylation - drug effects; PPAR alpha - genetics; PPARα; Ribosomal Protein S6 Kinases, 70-kDa - metabolism; Signal Transduction - drug effects; Sirolimus - pharmacology; SREBP1C; Sterol Regulatory Element Binding Protein 1 - genetics; TOR Serine-Threonine Kinases - metabolism; Triglycerides - metabolism; SREBP1C; mTOR pathway; triglycerides metabolism; dibutyltin dilaurate (DBTD); PPARα