The requirement for eukaryotic initiation factor 4A (eIF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure - SVITKIN, YURI V.; PAUSE, ARNIM; HAGHIGHAT, ASHKAN; PYRONNET, STÉPHANE; WITHERELL, GARY; BELSHAM, GRAHAM J.; SONENBERG, NAHUM (RNA (Cambridge), 2001)
Keywords: 5' Untranslated Regions - chemistry; Animals; Base Sequence; Conserved Sequence; Eukaryotic Initiation Factor-4A; initiation factor eIF-4A; initiation factor eIF-4B; initiation factor eIF-4F; initiation factor eIF-4G; Mice; Molecular Sequence Data; Mutation; Nuclear Cap-Binding Protein Complex; Nucleic Acid Conformation; Peptide Initiation Factors - genetics; Peptide Initiation Factors - metabolism; Phosphoproteins - metabolism; Picornaviridae - genetics; Picornavirus; Protein Binding; Protein Biosynthesis; Ribosomes - metabolism; RNA Caps; RNA Helicases - metabolism; RNA, Messenger - chemistry; RNA, Messenger - metabolism; RNA, Viral - genetics; RNA, Viral - metabolism; Saccharomyces cerevisiae Proteins; translation initiation; RNA helicases; RNA secondary structure; eIF4A; dominant-negative mutants