Does beta-lactoglobulin occur in human milk?

Although beta-lactoglobulin (beta-lg) has been considered to be absent from human milk, recent results of other workers, based on immunological reactions between human milk and rabbit antiserum to bovine beta-lg, suggest that this protein may be present. Although our results show similar immunologic...

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Published inJournal of dairy research Vol. 52; no. 2; pp. 249 - 254
Main Authors Brignon, G, Chtourou, A, Ribadeau-Dumas, B
Format Journal Article
LanguageEnglish
Published England 01.05.1985
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Abstract Although beta-lactoglobulin (beta-lg) has been considered to be absent from human milk, recent results of other workers, based on immunological reactions between human milk and rabbit antiserum to bovine beta-lg, suggest that this protein may be present. Although our results show similar immunological reactions, we consider that lactoferrin is responsible for these, as it was the only reactive protein species which could be prepared to homogeneity. Indeed two types of antibodies were found by ELISA test in the antisera to bovine beta-lg. One of them would be able to bind loosely to human lactoferrin, but its binding sites would not be antigenic in the rabbit.
AbstractList Although beta-lactoglobulin (beta-lg) has been considered to be absent from human milk, recent results of other workers, based on immunological reactions between human milk and rabbit antiserum to bovine beta-lg, suggest that this protein may be present. Although our results show similar immunological reactions, we consider that lactoferrin is responsible for these, as it was the only reactive protein species which could be prepared to homogeneity. Indeed two types of antibodies were found by ELISA test in the antisera to bovine beta-lg. One of them would be able to bind loosely to human lactoferrin, but its binding sites would not be antigenic in the rabbit.
Author Ribadeau-Dumas, B
Brignon, G
Chtourou, A
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Snippet Although beta-lactoglobulin (beta-lg) has been considered to be absent from human milk, recent results of other workers, based on immunological reactions...
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StartPage 249
SubjectTerms Animals
beta-lactoglobulin
breast milk
Cattle - immunology
Chromatography, Affinity
Electrophoresis, Polyacrylamide Gel
Enzyme-Linked Immunosorbent Assay
Immune Sera
Immunoelectrophoresis
Lactoferrin - analysis
Lactoglobulins - analysis
Milk Proteins - analysis
Milk, Human - analysis
Rabbits - immunology
Title Does beta-lactoglobulin occur in human milk?
URI https://www.ncbi.nlm.nih.gov/pubmed/4008713
Volume 52
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