Clinical Expression of Leber Hereditary Optic Neuropathy Is Affected by the Mitochondrial DNA–Haplogroup Background - Hudson, Gavin; Carelli, Valerio; Spruijt, Liesbeth; Gerards, Mike; Mowbray, Catherine; Achilli, Alessandro; Pyle, Angela; Elson, Joanna; Howell, Neil; La Morgia, Chiara; Valentino, Maria Lucia; Huoponen, Kirsi; et al. (American journal of human genetics, 2007)
Keywords: Adult; Biological and medical sciences; Blindness - genetics; DNA, Mitochondrial; Female; Fundamental and applied biological sciences. Psychology; Gene Frequency; General aspects. Genetic counseling; Genetic Variation; Genetics; Genetics of eukaryotes. Biological and molecular evolution; Haplotypes; Humans; Male; Medical genetics; Medical sciences; Mitochondrial DNA; Molecular and cellular biology; Mutation; Neurological disorders; Optic Atrophy, Hereditary, Leber - genetics; Penetrance; Risk Factors; Sex Factors; Human; Haplogroup; Genetics; Leber optic neuropathy; Mitochondrial DNA; Gene expression; Hereditary